Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 19/20 | 0.72 |
| ▸ | HTR1B | P28222 | 19/20 | 0.72 |
| ▸ | MPO | P05164 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6973429 | 0.84 | HTR1D (0.73) | HTR1DHTR1B | |
| SCHEMBL6973431 | 0.81 | HTR1D (0.66) | HTR1DHTR1BMPO | |
| SCHEMBL6969966 | 0.80 | HTR1D (0.67) | HTR1DHTR1BMPO | |
| SCHEMBL6965775 | 0.79 | HTR1D (0.68) | HTR1DHTR1B | |
| SCHEMBL6971173 | 0.78 | SLC6A4 (0.60) | HTR1DHTR1B | |
| SCHEMBL7006008 | 0.76 | HTR1D (0.62) | HTR1DHTR1BMPO | |
| SCHEMBL6964332 | 0.76 | HTR1D (0.59) | HTR1DHTR1B | |
| SCHEMBL20461312 | 0.76 | BRD4 (0.60) | HTR1DHTR1BMPO | |
| SCHEMBL7010593 | 0.76 | HTR1D (0.61) | HTR1DHTR1BMPO | |
| SCHEMBL8506288 | 0.75 | HTR1D (1.00) | HTR1DHTR1BMPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0944595-B1 | 5-CYCLO INDOLE COMPOUNDS AS 5-HT1D RECEPTOR LIGANDS | NPS ALLELIX CORP (CA) | 2003-10-01 | — | — | EP | claimed |
| EP-0944595-B1 | 5-CYCLO INDOLE COMPOUNDS AS 5-HT1D RECEPTOR LIGANDS | NPS ALLELIX CORP (CA) | 2003-10-01 | — | — | EP | disclosed |
| US-5998438-A | SEROTONIN RECEPTOR ANTAGONIST; HEADACHE THERAPY | ALLELIX BIOPHARMACEUTICALS, INC. (CA) | 1999-12-07 | — | — | US | disclosed |