Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 4/20 | 0.60 |
| ▸ | HTR1D | P28221 | 10/20 | 0.48 |
| ▸ | HTR1B | P28222 | 10/20 | 0.48 |
| ▸ | HTR6 | P50406 | 5/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6973426 | 0.85 | SLC6A4 (0.57) | SLC6A4HTR1DHTR1BHTR6 | |
| SCHEMBL7006006 | 0.78 | SLC6A4 (0.54) | SLC6A4HTR1DHTR1BHTR6 | |
| SCHEMBL6971174 | 0.78 | HTR1D (0.72) | HTR1DHTR1B | |
| SCHEMBL8506286 | 0.78 | SLC6A4 (0.67) | SLC6A4HTR1DHTR1BHTR6 | |
| SCHEMBL7010589 | 0.77 | SLC6A4 (0.53) | SLC6A4HTR1DHTR1BHTR6 | |
| SCHEMBL8506913 | 0.77 | SLC6A4 (0.70) | SLC6A4HTR1DHTR1BHTR6 | |
| SCHEMBL6968677 | 0.77 | SLC6A4 (0.70) | SLC6A4HTR1DHTR1BHTR6 | |
| SCHEMBL8686768 | 0.77 | HTR1D (0.64) | SLC6A4HTR1DHTR1BHTR6 | |
| SCHEMBL8894945 | 0.77 | SLC6A4 (0.60) | SLC6A4HTR1DHTR1BHTR6 | |
| SCHEMBL6969966 | 0.77 | HTR1D (0.67) | SLC6A4HTR1DHTR1BHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0944595-B1 | 5-CYCLO INDOLE COMPOUNDS AS 5-HT1D RECEPTOR LIGANDS | NPS ALLELIX CORP (CA) | 2003-10-01 | — | — | EP | claimed |
| EP-0944595-B1 | 5-CYCLO INDOLE COMPOUNDS AS 5-HT1D RECEPTOR LIGANDS | NPS ALLELIX CORP (CA) | 2003-10-01 | — | — | EP | disclosed |
| US-5998438-A | SEROTONIN RECEPTOR ANTAGONIST; HEADACHE THERAPY | ALLELIX BIOPHARMACEUTICALS, INC. (CA) | 1999-12-07 | — | — | US | disclosed |