Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 4/20 | 0.58 |
| ▸ | HTR1D | P28221 | 2/20 | 0.42 |
| ▸ | HTR6 | P50406 | 13/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6977592 | 0.84 | SLC6A4 (0.56) | SLC6A4HTR1DHTR6 | |
| SCHEMBL6971254 | 0.81 | MPO (0.55) | HTR1D | |
| SCHEMBL6964357 | 0.81 | SLC6A4 (0.62) | SLC6A4HTR1DHTR6 | |
| SCHEMBL6962932 | 0.79 | SLC6A4 (0.66) | SLC6A4HTR1DHTR6 | |
| SCHEMBL6969904 | 0.79 | SLC6A4 (0.60) | SLC6A4HTR1DHTR6 | |
| SCHEMBL6965894 | 0.79 | HTR1D (0.52) | SLC6A4HTR1DHTR6 | |
| SCHEMBL6974695 | 0.78 | SLC6A4 (0.65) | SLC6A4HTR1DHTR6 | |
| SCHEMBL6970056 | 0.76 | SLC6A4 (0.61) | SLC6A4HTR1DHTR6 | |
| SCHEMBL8506913 | 0.76 | SLC6A4 (0.70) | SLC6A4HTR1DHTR6 | |
| SCHEMBL6968677 | 0.76 | SLC6A4 (0.70) | SLC6A4HTR1DHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0944595-B1 | 5-CYCLO INDOLE COMPOUNDS AS 5-HT1D RECEPTOR LIGANDS | NPS ALLELIX CORP (CA) | 2003-10-01 | — | — | EP | claimed |
| US-5998438-A | SEROTONIN RECEPTOR ANTAGONIST; HEADACHE THERAPY | ALLELIX BIOPHARMACEUTICALS, INC. (CA) | 1999-12-07 | — | — | US | claimed |
| EP-0944595-B1 | 5-CYCLO INDOLE COMPOUNDS AS 5-HT1D RECEPTOR LIGANDS | NPS ALLELIX CORP (CA) | 2003-10-01 | — | — | EP | disclosed |
| US-5998438-A | SEROTONIN RECEPTOR ANTAGONIST; HEADACHE THERAPY | ALLELIX BIOPHARMACEUTICALS, INC. (CA) | 1999-12-07 | — | — | US | disclosed |