SCHEMBL697154

SCHEMBL697154

NNc1cccnn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL1618796 0.98
Hydrochloric Acid SCHEMBL11346788 0.98 GOT1 (0.95)
Bicarbonate SCHEMBL28194705 0.88 GOT1 (0.77)
SCHEMBL27539492 0.83 GOT1 (0.69)
SCHEMBL11837124 0.81
SCHEMBL29163817 0.79 GOT1 (0.65)
Hydrochloric Acid SCHEMBL11823953 0.76 GOT1 (0.57)
SCHEMBL976075 0.75
SCHEMBL16306329 0.75
SCHEMBL84649 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 238 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114829386-A Method for treating and/or preventing hypersomnia 洛桑大学 2022-07-29 CN claimed
US-20170095474-A1 COMPOUNDS AND METHODS FOR TREATING MULTIPLE SCLEROSIS PURDUE RESEARCH FOUNDATION (US) 2017-04-06 US claimed
US-20170065584-A1 COMPOSITIONS AND USES THEREOF TO AMELIORATE PAIN PURDUE RESEARCH FOUNDATION (US) 2017-03-09 US claimed
US-9517237-B2 Compounds and methods for treating multiple sclerosis PURDUE RESEARCH FOUNDATION (US) 2016-12-13 US claimed
US-9498477-B2 Compositions and uses thereof to ameliorate pain PURDUE RESEARCH FOUNDATION (US) 2016-11-22 US claimed
WO-2016153874-A1 COMPOSITIONS AND METHODS FOR TREATING PARKINSON'S DISEASE PURDUE RESEARCH FOUNDATION (US) 2016-09-29 WO claimed
US-20150246041-A1 COMPOUNDS AND METHODS FOR TREATING MULTIPLE SCLEROSIS NEURO VIGOR LLC (US) 2015-09-03 US claimed
US-9056109-B2 Compounds and methods for treating multiple sclerosis PURDUE RESEARCH FOUNDATION (US) 2015-06-16 US claimed
US-20150112061-A1 COMPOSITIONS AND USES THEREOF TO AMELIORATE PAIN PURDUE RESEARCH FOUNDATION (US) 2015-04-23 US claimed
US-8946220-B2 Compositions and uses thereof to ameliorate pain PURDUE RESEARCH FOUNDATION (US) 2015-02-03 US claimed
EP-0581805-A1 NOVEL PYRIDAZINES BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) 1994-02-09 EP claimed
WO-1992019602-A1 NOVEL PYRIDAZINES BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) 1992-11-12 WO claimed
EP-0510562-A1 Pyridazines Byk Gulden Lomberg Chemische Fabrik GmbH (DE) 1992-10-28 EP claimed
CN-1060843-A TRIAZOLOPYRIDAZINE DERIVATES RHONE POULENC AGROCHIMIE (FR) 1992-05-06 CN claimed
EP-0483027-A2 Triazolopyridazines, methods for their preparation, their use as herbicides and intermediates RHONE-POULENC AGROCHIMIE (FR) 1992-04-29 EP claimed
EP-0097202-B1 HYDRAZINOPYRIDAZINE COMPOUND, PROCESS FOR PRODUCTION THEREOF, AND USE THEREOF AS MEDICAMENT TEIKOKU HORMONE MFG. CO., LTD. (JP) 1987-11-19 EP claimed
US-4599333-A HYPOTENSIVE AGENTS TEIKOKU HORMONE MFG. CO., LTD. (JP) 1986-07-08 US claimed
EP-0097202-A1 Hydrazinopyridazine compound, process for production thereof, and use thereof as medicament TEIKOKU HORMONE MFG. CO., LTD. (JP) 1984-01-04 EP claimed
EP-0007930-A1 Arylpyridazinylhydrazine salt, processes for preparing it and pharmaceutical compositions containing it. SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) 1980-02-20 EP claimed
US-4086343-A Acylated hydrazinopyridazine antihypertensives I.S.F. SPA (IT) 1978-04-25 US claimed