Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.59 |
| ▸ | ACHE | P22303 | 8/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6957953 | 0.94 | EPHX1 (0.55) | EPHX1ACHETDP1KDM4EMAPK1 | |
| SCHEMBL294319 | 0.85 | — | — | |
| SCHEMBL7252127 | 0.84 | EPHX1 (0.77) | EPHX1ACHETDP1KDM4EMAPK1 | |
| SCHEMBL7788569 | 0.82 | EPHX1 (0.82) | EPHX1ACHETDP1KDM4EMAPK1 | |
| SCHEMBL717081 | 0.82 | EPHX1 (0.82) | EPHX1ACHETDP1KDM4EMAPK1 | |
| SCHEMBL7788937 | 0.82 | EPHX1 (0.82) | EPHX1ACHETDP1KDM4EMAPK1 | |
| SCHEMBL7788927 | 0.82 | EPHX1 (0.82) | EPHX1ACHETDP1KDM4EMAPK1 | |
| SCHEMBL14252129 | 0.82 | EPHX1 (0.82) | EPHX1ACHETDP1KDM4EMAPK1 | |
| SCHEMBL7996315 | 0.82 | EPHX1 (0.57) | EPHX1ACHETDP1KDM4EMAPK1 | |
| SCHEMBL6448286 | 0.81 | TDP1 (0.64) | EPHX1TDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015095780-A1 | TOLL-LIKE RECEPTOR 8 AGONISTS | THE UNIVERSITY OF KANSAS (US) | 2015-06-25 | — | — | WO | disclosed |
| WO-2015023958-A1 | TOLL-LIKE RECEPTOR AGONISTS | THE UNIVERSITY OF KANSAS (US) | 2015-02-19 | — | — | WO | disclosed |
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |