Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 5/20 | 0.82 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 7/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL717081 | 1.00 | EPHX1 (0.82) | EPHX1KDM4EMAPK1HIF1ATDP1 | |
| SCHEMBL7788927 | 1.00 | EPHX1 (0.82) | EPHX1KDM4EMAPK1HIF1ATDP1 | |
| SCHEMBL7788569 | 1.00 | EPHX1 (0.82) | EPHX1KDM4EMAPK1HIF1ATDP1 | |
| SCHEMBL7788937 | 1.00 | EPHX1 (0.82) | EPHX1KDM4EMAPK1HIF1ATDP1 | |
| SCHEMBL7252127 | 0.97 | EPHX1 (0.77) | EPHX1KDM4EMAPK1HIF1ATDP1 | |
| SCHEMBL23735485 | 0.93 | EPHX1 (0.72) | EPHX1KDM4EMAPK1HIF1ATDP1 | |
| SCHEMBL14433357 | 0.92 | EPHX1 (0.70) | EPHX1KDM4EMAPK1HIF1ATDP1 | |
| SCHEMBL13387440 | 0.91 | EPHX1 (1.00) | EPHX1ACHE | |
| SCHEMBL13387508 | 0.91 | EPHX1 (1.00) | EPHX1ACHE | |
| SCHEMBL22693961 | 0.91 | EPHX1 (1.00) | EPHX1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8927763-B2 | Method for preparing aliphatic diisocyanate | UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY (KR) | 2015-01-06 | — | — | US | claimed |
| US-20140303399-A1 | METHOD FOR PREPARING ALIPHATIC DIISOCYANATE | UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY (KR) | 2014-10-09 | — | — | US | claimed |
| CN-103687847-B | The manufacturing method of isocyanate compound | 宇部兴产株式会社 | 2019-04-02 | — | — | CN | disclosed |
| US-8927763-B2 | Method for preparing aliphatic diisocyanate | UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY (KR) | 2015-01-06 | — | — | US | disclosed |
| US-20140303399-A1 | METHOD FOR PREPARING ALIPHATIC DIISOCYANATE | UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY (KR) | 2014-10-09 | — | — | US | disclosed |
| US-7341815-B2 | Recording can be effected at a high sensitivity and in which scattering of the recording layer due to ablation is suppressed | FUJIFILM CORPORATION (JP) | 2008-03-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140303399-A1 | METHOD FOR PREPARING ALIPHATIC DIISOCYANATE | ALKBH3, DDC, ALKBH5 | EPHX1 3411/4885KDM4E 104/4885MAPK1 4108/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.