SCHEMBL6971614

SCHEMBL6971614

[CH2]OC(=O)C(C#N)OCCC

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6965596 0.89 ALDH1A1 (0.38) ALDH1A1TSHR
SCHEMBL6964932 0.79 TDP1 (0.31)
SCHEMBL27383900 0.73 ALDH1A1 (0.39) ALDH1A1TSHR
SCHEMBL6964563 0.71
SCHEMBL667294 0.69 HCAR2 (0.34) ALDH1A1TSHR
SCHEMBL28738580 0.69 ALDH1A1 (0.38) ALDH1A1TSHR
SCHEMBL6875291 0.69 ALDH1A1 (0.44) ALDH1A1TSHR
SCHEMBL5011157 0.68 ALDH1A1 (0.41) ALDH1A1TSHR
SCHEMBL6965392 0.68 ALDH1A1 (0.38) ALDH1A1TSHR
SCHEMBL11451905 0.66 HCAR2 (0.38) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1329160-A2 4-ACYLAMINOPYRAZOLE DERIVATIVES Sankyo Company, Limited (JP) 2003-07-23 EP disclosed