Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | CCKBR | P32239 | 1/20 | 0.35 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 2/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.33 |
| ▸ | RORB | Q92753 | 1/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.31 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL260609 | 0.85 | ALDH1A1 (0.44) | PRMT5ALDH1A1HSD17B10NPC1RAB9A | |
| SCHEMBL3623107 | 0.84 | PRMT5 (0.43) | PRMT5ALDH1A1HSD17B10NPC1RAB9A | |
| SCHEMBL4326134 | 0.84 | PRMT5 (0.43) | PRMT5ALDH1A1HSD17B10NPC1RAB9A | |
| SCHEMBL8592028 | 0.84 | PRMT5 (0.43) | PRMT5ALDH1A1HSD17B10NPC1RAB9A | |
| SCHEMBL13860748 | 0.84 | PRMT5 (0.43) | PRMT5ALDH1A1HSD17B10NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL1757952 | 0.82 | PRMT5 (0.42) | PRMT5ALDH1A1HSD17B10NPC1RAB9A | |
| SCHEMBL27595024 | 0.81 | PRMT5 (0.41) | PRMT5ALDH1A1HSD17B10NPC1RAB9A | |
| SCHEMBL25110231 | 0.80 | PRMT5 (0.48) | PRMT5 | |
| SCHEMBL6054736 | 0.80 | PRMT5 (0.40) | PRMT5ALDH1A1HSD17B10NPC1RAB9A | |
| SCHEMBL23216350 | 0.80 | PRMT5 (0.40) | PRMT5ALDH1A1HSD17B10CCKBRMAPK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |