SCHEMBL6971637

SCHEMBL6971637

NCNCCCC1CCCCC1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 4/20 0.54
CYP1A2 P05177 1/20 0.46
KDM1A O60341 1/20 0.39
MAOA P21397 1/20 0.39
MAOB P27338 1/20 0.39
EPHX1 P07099 2/20 0.35
ADH1B P00325 1/20 0.34
ADH1C P00326 1/20 0.34
ADH1A P07327 1/20 0.34
ADH4 P08319 1/20 0.34
ADH7 P40394 1/20 0.34
TLR7 Q9NYK1 1/20 0.33
HPGD P15428 1/20 0.33
RAD52 P43351 1/20 0.33
KDM5A P29375 1/20 0.33
KDM4C Q9H3R0 1/20 0.33
PHF8 Q9UPP1 1/20 0.33
KDM2A Q9Y2K7 1/20 0.33
NMT2 O60551 1/20 0.33
NMT1 P30419 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6967478 0.98 SIGMAR1 (0.50) SIGMAR1CYP1A2KDM1AMAOAMAOB
SCHEMBL6967853 0.94 SIGMAR1 (0.57) SIGMAR1CYP1A2KDM1AMAOAMAOB
SCHEMBL6974143 0.91 SIGMAR1 (0.54) SIGMAR1CYP1A2KDM1AMAOAMAOB
SCHEMBL6964057 0.89
SCHEMBL23131807 0.87 SIGMAR1 (0.59) SIGMAR1CYP1A2KDM1AMAOAMAOB
SCHEMBL21173520 0.87 SIGMAR1 (0.59) SIGMAR1CYP1A2KDM1AMAOAMAOB
SCHEMBL18531456 0.87 SIGMAR1 (0.59) SIGMAR1CYP1A2KDM1AMAOAMAOB
SCHEMBL18823178 0.87 SIGMAR1 (0.59) SIGMAR1CYP1A2KDM1AMAOAMAOB
SCHEMBL5057409 0.87 SIGMAR1 (0.59) SIGMAR1CYP1A2KDM1AMAOAMAOB
SCHEMBL18430893 0.87 SIGMAR1 (0.59) SIGMAR1CYP1A2KDM1AMAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0870765-B1 AMINOTHIAZOLE DERIVATIVES, DRUG CONTAINING THE SAME AND INTERMEDIATE IN THE PRODUCTION OF THE COMPOUNDS ZERIA PHARM CO LTD (JP) 2003-11-19 EP disclosed
US-5981557-A HAVING IMPROVING EFFECTS ON THE DYSMOTILITY IN THE GASTROINTESTINAL TRACT ZERIA PHARMACEUTICAL CO., LTD. (JP) 1999-11-09 US disclosed
EP-0870765-A1 AMINOTHIAZOLE DERIVATIVES, DRUG CONTAINING THE SAME AND INTERMEDIATE IN THE PRODUCTION OF THE COMPOUNDS ZERIA PHARMACEUTICAL CO., LTD. (JP) 1998-10-14 EP disclosed