⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11148147 | 1.00 | TSHR (0.42) | — | |
| SCHEMBL2315801 | 0.97 | — | — | |
| SCHEMBL6702933 | 0.89 | — | — | |
| SCHEMBL11148145 | 0.79 | TSHR (0.42) | — | |
| SCHEMBL292061 | 0.76 | TSHR (0.44) | — | |
| SCHEMBL8379912 | 0.76 | TSHR (0.44) | — | |
| SCHEMBL8053585 | 0.76 | TSHR (0.44) | — | |
| SCHEMBL8378823 | 0.76 | TSHR (0.44) | — | |
| SCHEMBL291758 | 0.76 | TSHR (0.44) | — | |
| SCHEMBL8377210 | 0.76 | TSHR (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105793343-B | Enhancer compositions and method | 罗宾逊兄弟有限公司 | 2018-05-22 | — | — | CN | disclosed |
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |