⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| O,O-Diethyl S-Hydrogen Phosphorothioate SCHEMBL600183 | 0.85 | — | — | |
| O,O-Diethyl S-Hydrogen Phosphorothioate SCHEMBL4585075 | 0.82 | PPARD (0.39) | — | |
| O,O-Diethyl S-Hydrogen Phosphorothioate SCHEMBL1502086 | 0.82 | PPARD (0.39) | — | |
| O,O-Diethyl S-Hydrogen Phosphorothioate SCHEMBL8429419 | 0.82 | PPARD (0.39) | — | |
| SCHEMBL28016343 | 0.79 | — | — | |
| SCHEMBL11590408 | 0.79 | — | — | |
| SCHEMBL17748479 | 0.78 | — | — | |
| O,O-Diethyl S-Hydrogen Phosphorothioate SCHEMBL28187474 | 0.78 | POLB (0.36) | — | |
| O,O-Diethyl S-Hydrogen Phosphorothioate SCHEMBL28542642 | 0.78 | TSHR (0.38) | — | |
| SCHEMBL7202962 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025052391-A1 | ANTISENSE OLIGONUCLEOTIDES TARGETING THE CFTR 3849+10 KILOBASE (KB) C->T SPLICING MUTATION | SPLISENSE LTD. (IL) | 2025-03-13 | — | — | WO | disclosed |
| CN-112778271-A | Molecules having pesticidal utility and compositions and methods related thereto | 美国陶氏益农公司 | 2021-05-11 | — | — | CN | disclosed |
| CN-112218530-A | Molecules having pesticidal utility and compositions and methods related thereto | 美国陶氏益农公司 | 2021-01-12 | — | — | CN | disclosed |
| CN-110257379-A | For treating the oligonucleotides of muscular dystrophy patient | 马林生物科技有限公司 | 2019-09-20 | — | — | CN | disclosed |
| CN-110267970-A | Materials for targeting various selected organs or tissues | 比奥马林技术公司 | 2019-09-20 | — | — | CN | disclosed |
| CN-104603271-B | Oligonucleotides for treating patients with muscular dystrophy | 马林生物科技有限公司 | 2019-07-19 | — | — | CN | disclosed |
| CN-104661664-A | Chiral control | WAVE LIFE SCIENCES PTY LTD | 2015-05-27 | — | — | CN | disclosed |
| EP-2851371-A1 | Glycoclusters and their pharmaceutical use as antibacterials | Centre National de la Recherche Scientifique (CNRS) (FR) | 2015-03-25 | — | — | EP | disclosed |
| CN-101495633-A | Composition and method for treatment of tumors | SANOFI AVENTIS (FR) | 2009-07-29 | — | — | CN | disclosed |
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |