Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 5/20 | 0.38 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.37 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| O,O-Diethyl S-Hydrogen Phosphorothioate SCHEMBL600183 | 0.97 | — | — | |
| O,O-Diethyl S-Hydrogen Phosphorothioate SCHEMBL4585075 | 0.94 | PPARD (0.39) | PPARDTSHRLPAR2LPAR3TDP1 | |
| O,O-Diethyl S-Hydrogen Phosphorothioate SCHEMBL1502086 | 0.94 | PPARD (0.39) | PPARDTSHRLPAR2LPAR3TDP1 | |
| O,O-Diethyl S-Hydrogen Phosphorothioate SCHEMBL28187474 | 0.88 | POLB (0.36) | PPARDTSHRLPAR2LPAR3ALDH1A1 | |
| O,O-Diethyl S-Hydrogen Phosphorothioate SCHEMBL28542642 | 0.88 | TSHR (0.38) | PPARDTSHRLPAR2LPAR3TDP1 | |
| O,O-Diethyl S-Hydrogen Phosphorothioate SCHEMBL28537561 | 0.86 | TSHR (0.36) | PPARDTSHRLPAR2LPAR3TDP1 | |
| O,O-Diethyl S-Hydrogen Phosphorothioate SCHEMBL28537563 | 0.86 | TSHR (0.36) | PPARDTSHRLPAR2LPAR3TDP1 | |
| SCHEMBL11597869 | 0.84 | LPAR3 (0.41) | PPARDTSHRLPAR2LPAR3TDP1 | |
| O,O-Diethyl S-Hydrogen Phosphorothioate SCHEMBL7784856 | 0.84 | CYP2C9 (0.33) | PPARDTSHRLPAR2LPAR3TDP1 | |
| O,O-Diethyl S-Hydrogen Phosphorothioate SCHEMBL27987724 | 0.83 | LPAR3 (0.42) | PPARDLPAR2LPAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-11181469-A | — | — | None | — | — | JP | disclosed |
| US-12312343-B2 | Rotomeric isomers of 4-alkyl-5-heteroaryl-3H-1,2-dithiole-3-thiones | ST IP HOLDING AG (CH) | 2025-05-27 | — | — | US | disclosed |
| EP-3853223-B1 | ROTOMERIC ISOMERS OF 4-ALKYL-5-HETEROARYL-3H-1,2- DITHIOLE-3-THIONES | ST IP HOLDING AG (CH) | 2025-01-01 | — | — | EP | disclosed |
| CN-117820371-A | Method for esterification of azanaphthalene ring-C2-thiophosphoric acid | 湖南科技学院 | 2024-04-05 | — | — | CN | disclosed |
| US-20230255961-A1 | Rotomeric Isomers of 4-Alkyl-5-Heteroaryl-3H-1,2-Dithiole-3-Thiones | ZPNE GROUP GMBH (CH) | 2023-08-17 | — | — | US | disclosed |
| CN-113694068-A | Rotamers of 4-alkyl-5-heteroaryl-3H-1, 2-dithiole-3-thiones | ST知识产权控股公司 | 2021-11-26 | — | — | CN | disclosed |
| EP-3853223-A1 | ROTOMERIC ISOMERS OF 4-ALKYL-5-HETEROARYL-3H-1,2- DITHIOLE-3-THIONES | ST IP Holding AG (CH) | 2021-07-28 | — | — | EP | disclosed |
| CN-113166127-A | Rotamers of 4-alkyl-5-heteroaryl-3H-1, 2-dithiole-3-thiones | ST知识产权控股公司 | 2021-07-23 | — | — | CN | disclosed |
| US-20210206751-A1 | Rotomeric Isomers of 4-alkyl-5-Heteroaryl-3H-1,2-Dithiole-3-Thiones | SUPPORTIVE THERAPEUTICS AG (CH) | 2021-07-08 | — | — | US | disclosed |
| WO-2020058767-A1 | ROTOMERIC ISOMERS OF 4-ALKYL-5-HETEROARYL-3H-1,2- DITHIOLE-3-THIONES | ST IP HOLDING AG (CH) | 2020-03-26 | — | — | WO | disclosed |
| JP-H11181469-A | COLD-ROLLING OIL | SUMITOMO METAL IND LTD | 1999-07-06 | — | — | JP | disclosed |
| US-5641888-A | Synthesis of an O,O' -diesters of thiophosphoric acid, an O-ester of thiophosphonic acid, or a thiophosphinic acid | BAYER AKTIENGESELLSCHAFT (DE) | 1997-06-24 | — | — | US | disclosed |
| EP-0723968-A2 | Process for the preparation of thiophosphoric acid 0,0'-diesters and their salts as well as their preparation | BAYER AG (DE) | 1996-07-31 | — | — | EP | disclosed |
| EP-0114055-B1 | THIOPHOSPHORIC ACID ESTERS | BASF Aktiengesellschaft (DE) | 1986-11-12 | — | — | EP | disclosed |
| EP-0001753-B1 | THIOPHOSPHORIC(PHOSPHONIC) ACID ESTERS, PROCESS FOR THEIR PREPARATION AND USE AS PESTICIDES | BASF Aktiengesellschaft (DE) | 1980-12-10 | — | — | EP | disclosed |
| US-4210592-A | INSECTICIDES, MITICIDES | MAKHTESHIM CHEMICAL WORKS, LTD. (IL) | 1980-07-01 | — | — | US | disclosed |
| US-4203977-A | PESTICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1980-05-20 | — | — | US | disclosed |
| EP-0001753-A1 | Thiophosphoric(phosphonic) acid esters, process for their preparation and use as pesticides | BASF Aktiengesellschaft (DE) | 1979-05-16 | — | — | EP | disclosed |
| US-3962431-A | Insecticidal use of O,O-dialkyl phosphorodithioate and phosphorothioate esters of oxazolidine-2,4-dione derivatives | HERCULES INCORPORATED (US) | 1976-06-08 | — | — | US | disclosed |
| US-3948944-A | INSECTICIDES, NEMATOCIDES, MITICIDES | VALINT JR PAUL L | 1976-04-06 | — | — | US | disclosed |