Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 5/20 | 0.45 |
| ▸ | CDK8 | P49336 | 5/20 | 0.45 |
| ▸ | CDK19 | Q9BWU1 | 5/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CDK9 | P50750 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | CSF1R | P07333 | 5/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | IKBKB | O14920 | 1/20 | 0.33 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.33 |
| ▸ | S100A4 | P26447 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6968247 | 0.88 | GAA (0.43) | CCNCCDK8CDK19GAAKDM4E | |
| SCHEMBL6978994 | 0.85 | CCNC (0.43) | CCNCCDK8CDK19GAAKDM4E | |
| SCHEMBL6970409 | 0.84 | GAA (0.44) | CCNCCDK8CDK19GAAKDM4E | |
| SCHEMBL6978646 | 0.75 | CCNC (0.59) | CCNCCDK8CDK19GAACDK9 | |
| SCHEMBL6980131 | 0.74 | CCNC (0.55) | CCNCCDK8CDK19GAACDK9 | |
| SCHEMBL6967359 | 0.72 | CCNC (0.56) | CCNCCDK8CDK19GAACDK9 | |
| SCHEMBL8195226 | 0.70 | GAA (0.43) | CCNCCDK8CDK19GAACDK9 | |
| SCHEMBL6975301 | 0.68 | CCNC (0.51) | CCNCCDK8CDK19GAACDK9 | |
| SCHEMBL7980960 | 0.65 | KDM4E (0.39) | KDM4EUSP2ALDH1A1TSHRKMT2A | |
| SCHEMBL7981965 | 0.64 | MAPT (0.37) | KDM4EUSP2ALDH1A1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1120415-B1 | SUBSTITUTED ISOXAZOLYLTHIOPHENE COMPOUNDS | TAISHO PHARMACEUTICAL CO LTD (JP) | 2003-07-23 | — | — | EP | disclosed |
| US-6355663-B1 | AN ENHANCING AGENT FOR THE ACTION OF CELL DIFFERENTIATION INDUCTION FACTORS FOR BONE DISORDERS AND NERVOUS SYSTEM DISORDERS | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2002-03-12 | — | — | US | disclosed |
| EP-1120415-A1 | SUBSTITUTED ISOXAZOLYLTHIOPHENE COMPOUNDS | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2001-08-01 | — | — | EP | disclosed |