Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6264553 | 0.77 | KDM4E (0.38) | MAPTPOLBKDM4EUSP2ALDH1A1 | |
| SCHEMBL12305011 | 0.76 | KDM4E (0.45) | MAPTPOLBKDM4EUSP2ALDH1A1 | |
| SCHEMBL7980960 | 0.73 | KDM4E (0.39) | MAPTPOLBKDM4EUSP2ALDH1A1 | |
| SCHEMBL8310371 | 0.69 | KDM4E (0.41) | MAPTPOLBKDM4EUSP2ALDH1A1 | |
| SCHEMBL12305013 | 0.69 | CSF1R (0.40) | MAPTPOLBKDM4EUSP2ALDH1A1 | |
| SCHEMBL7985184 | 0.69 | CSF1R (0.43) | MAPTKDM4EUSP2ALDH1A1TSHR | |
| SCHEMBL3342160 | 0.67 | KDM4E (0.49) | MAPTPOLBKDM4EALDH1A1CYP1A2 | |
| SCHEMBL8305274 | 0.66 | KDM4E (0.40) | MAPTKDM4EUSP2ALDH1A1TSHR | |
| SCHEMBL12603538 | 0.66 | CSF1R (0.43) | MAPTKDM4EUSP2ALDH1A1TSHR | |
| SCHEMBL8058708 | 0.66 | BRD4 (0.50) | KDM4EUSP2ALDH1A1TSHRCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245716-B1 | LOW DOSAGE; NONPHYTOTOXIC | NIPPON SODA CO., LTD. (JP) | 2001-06-12 | — | — | US | disclosed |