Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 3/20 | 0.39 |
| ▸ | AVPR2 | P30518 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.36 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9414267 | 0.90 | AVPR2 (0.40) | AVPR2ALDH1A1POLBLMNAAVPR1A | |
| SCHEMBL6970774 | 0.89 | AVPR2 (0.47) | CCKBRAVPR2AVPR1ARAB9A | |
| SCHEMBL6959421 | 0.88 | AVPR2 (0.42) | AVPR2ALDH1A1POLBAVPR1AMEN1 | |
| SCHEMBL6968503 | 0.88 | AVPR2 (0.48) | AVPR2AVPR1A | |
| SCHEMBL6959660 | 0.83 | AVPR2 (0.50) | CCKBRAVPR2AVPR1A | |
| SCHEMBL6971575 | 0.82 | AVPR2 (0.42) | AVPR2ALDH1A1POLBLMNAAVPR1A | |
| SCHEMBL6961515 | 0.81 | AVPR2 (0.53) | AVPR2AVPR1A | |
| SCHEMBL6972403 | 0.80 | AVPR2 (0.44) | CCKBRAVPR2POLBLMNATSHR | |
| SCHEMBL6970420 | 0.80 | AVPR2 (0.49) | AVPR2AVPR1A | |
| SCHEMBL6966416 | 0.80 | AVPR2 (0.53) | CCKBRAVPR2AVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620216-B1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-01-08 | — | — | EP | disclosed |
| EP-0620216-A1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |