Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 5/20 | 0.42 |
| ▸ | AVPR1A | P37288 | 4/20 | 0.42 |
| ▸ | AVPR1B | P47901 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | WDR5 | P61964 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6964131 | 0.90 | MEN1 (0.42) | AVPR2AVPR1AAVPR1BALDH1A1MAPT | |
| SCHEMBL6967250 | 0.89 | AVPR2 (0.46) | AVPR2AVPR1AAVPR1B | |
| SCHEMBL6957577 | 0.87 | AVPR1A (0.49) | AVPR2AVPR1AAVPR1B | |
| SCHEMBL6970606 | 0.87 | AVPR2 (0.40) | AVPR2AVPR1AAVPR1BALDH1A1MAPT | |
| SCHEMBL6961515 | 0.85 | AVPR2 (0.53) | AVPR2AVPR1AAVPR1B | |
| SCHEMBL6972403 | 0.83 | AVPR2 (0.44) | AVPR2AVPR1AAVPR1BLMNAPOLB | |
| SCHEMBL9414294 | 0.82 | AVPR1A (0.47) | AVPR2AVPR1AAVPR1BLMNA | |
| SCHEMBL6972088 | 0.82 | CCKBR (0.39) | AVPR2AVPR1AALDH1A1MAPTMEN1 | |
| SCHEMBL6965585 | 0.81 | AVPR1A (0.51) | AVPR2AVPR1AAVPR1B | |
| SCHEMBL6968503 | 0.81 | AVPR2 (0.48) | AVPR2AVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620216-B1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-01-08 | — | — | EP | disclosed |
| US-5521170-A | VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-28 | — | — | US | disclosed |
| EP-0620216-A1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |