Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SLC9A3 | P48764 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 5/20 | 0.36 |
| ▸ | BCL2 | P10415 | 2/20 | 0.36 |
| ▸ | BECN1 | Q14457 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL297319 | 0.87 | MEN1 (0.54) | TNKSMEN1KMT2ANPC1RAB9A | |
| Hydrochloric Acid SCHEMBL30765001 | 0.85 | TNKS (0.52) | TNKSMEN1KMT2ANPC1RAB9A | |
| SCHEMBL27645807 | 0.85 | TNKS (0.52) | TNKSMEN1KMT2ANPC1RAB9A | |
| Piperidine SCHEMBL3263324 | 0.81 | TNKS (0.48) | TNKSMEN1KMT2ANPC1RAB9A | |
| SCHEMBL27923814 | 0.81 | TNKS (0.45) | TNKSMEN1KMT2ANPC1RAB9A | |
| SCHEMBL27365143 | 0.81 | TNKS (0.47) | TNKSMEN1KMT2ANPC1RAB9A | |
| Boric Acid SCHEMBL27822670 | 0.80 | TNKS (0.49) | TNKSMEN1KMT2ANPC1RAB9A | |
| SCHEMBL991958 | 0.80 | MEN1 (0.50) | TNKSMEN1KMT2ANPC1RAB9A | |
| Pyrrolidine SCHEMBL5240466 | 0.79 | TNKS (0.49) | TNKSMEN1KMT2ANPC1RAB9A | |
| Piperazine SCHEMBL3193494 | 0.79 | TNKS (0.51) | TNKSMEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1154645-C | S-oxide and S, S-dioxide tetrahydrothiopyran phenyloxazolidinones | �������Ŷ���Լ��������˾ | 2004-06-23 | — | — | CN | disclosed |
| EP-1036074-B1 | S-OXIDE TETRAHYDROTHIOPYRAN PHENYLOXAZOLIDINONES | UPJOHN CO (US) | 2003-01-29 | — | — | EP | disclosed |
| EP-1254906-A1 | Tetrahydrothiopyran phenyloxazolidinone S,S-dioxides | PHARMACIA & UPJOHN COMPANY (US) | 2002-11-06 | — | — | EP | disclosed |
| EP-1254906-A1 | Tetrahydrothiopyran phenyloxazolidinone S,S-dioxides | PHARMACIA & UPJOHN COMPANY (US) | 2002-11-06 | — | — | EP | disclosed |
| US-6265178-B1 | Assay for determining oxazolidinone antibiotics having minimum monoamine oxidase inhibitory activity | PHARMACIA & UPJOHN COMPANY | 2001-07-24 | — | — | US | disclosed |
| CN-1278817-A | S-oxide and S, S-dioxide tetrahydrothiopyran phenyloxazolidinones | UPJOHN CO (US) | 2001-01-03 | — | — | CN | disclosed |
| EP-1036074-A1 | S-OXIDE AND S,S-DIOXIDE TETRAHYDROTHIOPYRAN PHENYLOXAZOLIDINONES | PHARMACIA & UPJOHN COMPANY (US) | 2000-09-20 | — | — | EP | disclosed |
| US-6083967-A | ANTIMICROBIAL AGENTS; ASSAY FOR DETERMINING THE INHIBITORY ACTIVITY OF OXAZOLIDINONES TO HUMAN MONOAMINE OXIDASE | PHARMACIA & UPJOHN COMPANY (US) | 2000-07-04 | — | — | US | disclosed |
| US-6083967-A | ANTIMICROBIAL AGENTS; ASSAY FOR DETERMINING THE INHIBITORY ACTIVITY OF OXAZOLIDINONES TO HUMAN MONOAMINE OXIDASE | PHARMACIA & UPJOHN COMPANY (US) | 2000-07-04 | — | — | US | disclosed |
| WO-1999029688-A1 | S-OXIDE AND S,S-DIOXIDE TETRAHYDROTHIOPYRAN PHENYLOXAZOLIDINONES | PHARMACIA & UPJOHN COMPANY (US) | 1999-06-17 | — | — | WO | disclosed |