SCHEMBL297319

SCHEMBL297319

O=C1OCCN1c1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.54
KMT2A Q03164 2/20 0.54
NPC1 O15118 1/20 0.54
RAB9A P51151 1/20 0.54
TNKS O95271 1/20 0.54
HSD11B1 P28845 1/20 0.47
KDM4E B2RXH2 2/20 0.44
GAA P10253 1/20 0.44
MAPT P10636 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
DDB1 Q16531 1/20 0.44
CRBN Q96SW2 1/20 0.44
SIGMAR1 Q99720 3/20 0.43
SLC9A3 P48764 1/20 0.43
LMNA P02545 1/20 0.42
BCL2 P10415 1/20 0.42
BECN1 Q14457 1/20 0.42
KDM1A O60341 1/20 0.42
NAAA Q02083 3/20 0.41
FAAH O00519 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27645807 0.98 TNKS (0.52) MEN1KMT2ANPC1RAB9ATNKS
Hydrochloric Acid SCHEMBL30765001 0.98 TNKS (0.52) MEN1KMT2ANPC1RAB9ATNKS
Boric Acid SCHEMBL27822670 0.93 TNKS (0.49) MEN1KMT2ANPC1RAB9ATNKS
Piperazine SCHEMBL3193494 0.91 TNKS (0.51) MEN1KMT2ANPC1RAB9ATNKS
Phosphoric Acid SCHEMBL455111 0.91 TNKS (0.48) MEN1KMT2ANPC1RAB9ATNKS
SCHEMBL27365143 0.89 TNKS (0.47) MEN1KMT2ANPC1RAB9ATNKS
SCHEMBL991958 0.88 MEN1 (0.50) MEN1KMT2ANPC1RAB9ATNKS
Pyrrolidine SCHEMBL5240466 0.88 TNKS (0.49) MEN1KMT2ANPC1RAB9ATNKS
SCHEMBL6972215 0.87 TNKS (0.45) MEN1KMT2ANPC1RAB9ATNKS
Piperidine SCHEMBL3263324 0.87 TNKS (0.48) MEN1KMT2ANPC1RAB9ATNKS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1049 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116041602-B Preparation and application of polymer material containing organic strong base 福州大学 2024-11-15 CN claimed
CN-117417272-B Preparation method of Boc-D-isoleucine 上海海皋科技有限公司 2024-08-13 CN claimed
CN-117417272-A Preparation method of Boc-D-isoleucine 上海海皋科技有限公司 2024-01-19 CN claimed
CN-116041602-A Preparation and application of polymer material containing organic strong base 福州大学 2023-05-02 CN claimed
CN-110934880-A Compositions containing mixtures of phenyl oxazolidinone derivatives and uses thereof 黄泳华 2020-03-31 CN claimed
CN-103339116-B Substituted n-valeramide compound, preparation method and application thereof SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) 2016-04-06 CN claimed
CN-103864707-B (S)-[3-(the fluoro-4-morpholinyl of 3-) phenyl-2-oxo-5-oxazolidinyl] methylamine preparation method YANTAI WANRUN PHARMACEUTICAL CO., LTD. (CN) 2015-11-04 CN claimed
CN-103864707-A Preparation method of (S)-[3-(3- fluoro-4-morpholinyl) phenyl-2-oxo-5-oxazolidinyl] methylamine YANTAI WANRUN PHARMACEUTICAL CO LTD 2014-06-18 CN claimed
US-20130288356-A1 SYSTEM FOR DETERMINING DRUG RESISTANCE IN MICROORGANISMS THE JOHNS HOPKINS UNIVERSITY 2013-10-31 US claimed
US-8481281-B2 Systems and methods for determining drug resistance in microorganisms THE JOHNS HOPKINS UNIVERSITY (US) 2013-07-09 US claimed
EP-0632022-B1 Process for the preparation of amino-substituted thioethers BAYER AG (DE) 1996-12-27 EP claimed
US-5536826-A OXAZOLIDINONE OR DERIVATIVE CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) 1996-07-16 US claimed
US-5491263-A DECYCLIZATION OF AN OXAZOLIDINONE WITH A SECONDARY AMINE OR A SECONDARY ALKANOLAMINE THE DOW CHEMICAL COMPANY (US) 1996-02-13 US claimed
EP-0672687-A1 Process for producing amino-functional cyclodextrin derivatives Consortium für elektrochemische Industrie GmbH (DE) 1995-09-20 EP claimed
US-5410081-A Process for the preparation of amino-substituted thioethers BAYER AKTIENGESELLSCHAFT (DE) 1995-04-25 US claimed
CN-1097739-A The preparation method of amino-substituted thioethers BAYER AG (DE) 1995-01-25 CN claimed
EP-0632022-A2 Process for the preparation of amino-substituted thioethers BAYER AG (DE) 1995-01-04 EP claimed
EP-0610265-A1 SUBSTITUTED ARYL- AND HETEROARYLPHENYLOXAZOLIDINONES USEFUL AS ANTIBACTERIAL AGENTS. UPJOHN CO (US) 1994-08-17 EP claimed
WO-1993009103-A1 SUBSTITUTED ARYL- AND HETEROARYLPHENYLOXAZOLIDINONES USEFUL AS ANTIBACTERIAL AGENTS THE UPJOHN COMPANY (US) 1993-05-13 WO claimed
EP-0417044-A2 Oxazolidinones and thiones as plantgrowth regulators CIBA-GEIGY AG (CH) 1991-03-13 EP claimed