Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 4/20 | 0.32 |
| ▸ | MAOA | P21397 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6967547 | 0.88 | MEN1 (0.35) | MEN1KMT2ANPSR1TDP1L3MBTL1 | |
| SCHEMBL6973521 | 0.87 | KMT2A (0.34) | MEN1KMT2ANPSR1TDP1L3MBTL1 | |
| SCHEMBL6962750 | 0.85 | MEN1 (0.39) | MEN1KMT2ANPSR1TDP1L3MBTL1 | |
| SCHEMBL8800399 | 0.84 | MEN1 (0.36) | MEN1KMT2ANPSR1TDP1L3MBTL1 | |
| SCHEMBL6960398 | 0.83 | MEN1 (0.38) | MEN1KMT2ANPSR1TDP1L3MBTL1 | |
| SCHEMBL6966584 | 0.83 | MEN1 (0.37) | MEN1KMT2ANPSR1TDP1L3MBTL1 | |
| SCHEMBL8800395 | 0.83 | KMT2A (0.35) | MEN1KMT2ANPSR1TDP1L3MBTL1 | |
| SCHEMBL8343051 | 0.82 | LMNA (0.34) | MEN1KMT2ANPSR1TDP1L3MBTL1 | |
| SCHEMBL6966777 | 0.78 | MEN1 (0.46) | MEN1KMT2ANPSR1TDP1L3MBTL1 | |
| SCHEMBL8343056 | 0.77 | MEN1 (0.35) | MEN1KMT2ANPSR1TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786455-B1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO (JP) | 2003-12-03 | — | — | EP | disclosed |
| US-6147097-A | METHOD FOR TREATING AIDS | SHIONOGI & CO., LTD. (JP) | 2000-11-14 | — | — | US | disclosed |
| US-5910506-A | IMIDAZOLE DERIVATIVES, E.G.5-(3,5-DICHLOROPHENYLTHIO)-1,2-DIMETHYL-4-ISOPROPYL-1H-IMIDAZOLE; VIRICIDES; AIDS; NONTOXIC | SHIONOGI & CO., LTD. (JP) | 1999-06-08 | — | — | US | disclosed |
| EP-0786455-A1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1997-07-30 | — | — | EP | disclosed |