Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 5/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.52 |
| ▸ | PDE4A | P27815 | 1/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.50 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.47 |
| ▸ | BRD2 | P25440 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.46 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.45 |
| ▸ | TUBB | P07437 | 1/20 | 0.45 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.45 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.45 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.45 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.45 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7016623 | 0.86 | BRD4 (0.63) | BRD4ALDH1A1CRBNPDE4APDE4B | |
| SCHEMBL7021672 | 0.85 | BRD4 (0.59) | BRD4ALDH1A1CRBNPDE4APDE4B | |
| SCHEMBL6955057 | 0.84 | BRD4 (0.57) | BRD4ALDH1A1CRBNPDE4APDE4B | |
| SCHEMBL6966461 | 0.81 | BRD4 (0.65) | BRD4ALDH1A1CRBNLMNANPSR1 | |
| SCHEMBL7353031 | 0.77 | PDE4A (0.75) | ALDH1A1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6201929 | 0.77 | BRD4 (0.60) | BRD4ALDH1A1CRBNLMNANPSR1 | |
| SCHEMBL23174997 | 0.77 | BRD4 (0.60) | BRD4ALDH1A1CRBNLMNANPSR1 | |
| SCHEMBL6958949 | 0.75 | AVPR1A (0.58) | BRD4ALDH1A1 | |
| SCHEMBL6976978 | 0.75 | PDE4A (0.62) | BRD4ALDH1A1PDE4APDE4BPDE4C | |
| SCHEMBL6202811 | 0.74 | BRD4 (0.60) | BRD4ALDH1A1CRBNLMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620216-B1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-01-08 | — | — | EP | disclosed |
| US-5521170-A | VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-28 | — | — | US | disclosed |
| EP-0620216-A1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |