Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 8/20 | 0.47 |
| ▸ | AVPR2 | P30518 | 7/20 | 0.47 |
| ▸ | OXTR | P30559 | 3/20 | 0.45 |
| ▸ | PRKACA | P17612 | 1/20 | 0.44 |
| ▸ | PRKACG | P22612 | 1/20 | 0.44 |
| ▸ | PRKACB | P22694 | 1/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6957920 | 0.86 | AVPR2 (0.43) | AVPR1AAVPR2ABCB11HTR1ACHRM1 | |
| SCHEMBL7345463 | 0.84 | AVPR1A (0.46) | AVPR1AAVPR2OXTRABCB11HTR1A | |
| SCHEMBL6965604 | 0.80 | AVPR2 (0.61) | AVPR1AAVPR2OXTRABCB11HTR1A | |
| SCHEMBL6962598 | 0.79 | AVPR2 (0.61) | AVPR1AAVPR2OXTRABCB11HTR1A | |
| SCHEMBL7345080 | 0.78 | AVPR2 (0.57) | AVPR1AAVPR2OXTRABCB11HTR1A | |
| SCHEMBL7347556 | 0.77 | AVPR1A (0.54) | AVPR1AAVPR2OXTRABCB11HTR1A | |
| SCHEMBL6969586 | 0.77 | AVPR2 (0.51) | AVPR1AAVPR2OXTR | |
| SCHEMBL4697098 | 0.76 | HDAC1 (0.42) | AVPR1AAVPR2 | |
| SCHEMBL4682585 | 0.76 | HDAC1 (0.42) | AVPR1AAVPR2ABCB11HTR1ACHRM1 | |
| SCHEMBL7353739 | 0.76 | AVPR1A (0.57) | AVPR1AAVPR2OXTRABCB11HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620216-B1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-01-08 | — | — | EP | disclosed |
| US-5521170-A | VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-28 | — | — | US | disclosed |
| EP-0620216-A1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |