Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 9/20 | 0.51 |
| ▸ | AVPR1A | P37288 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | OXTR | P30559 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6965409 | 0.85 | SMN1; SMN2 (0.47) | NPC1RAB9AALDH1A1POLBMAPT | |
| SCHEMBL6960127 | 0.81 | NPSR1 (0.49) | AVPR2AVPR1ANPC1RAB9AALDH1A1 | |
| SCHEMBL6955225 | 0.80 | AVPR2 (0.73) | AVPR2AVPR1ANPC1RAB9AALDH1A1 | |
| SCHEMBL6963125 | 0.77 | AVPR2 (0.69) | AVPR2AVPR1AOXTR | |
| SCHEMBL6972707 | 0.77 | AVPR1A (0.47) | AVPR2AVPR1AOXTR | |
| SCHEMBL7343228 | 0.76 | AVPR2 (0.63) | AVPR2AVPR1ANPC1RAB9AALDH1A1 | |
| SCHEMBL7345463 | 0.75 | AVPR1A (0.46) | AVPR2AVPR1AOXTR | |
| SCHEMBL6972107 | 0.74 | NOTUM (0.46) | AVPR2AVPR1ANPC1RAB9AALDH1A1 | |
| SCHEMBL7080843 | 0.74 | AVPR2 (0.47) | AVPR2AVPR1ANPC1RAB9AALDH1A1 | |
| SCHEMBL7080842 | 0.74 | AVPR2 (0.47) | AVPR2AVPR1ANPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620216-B1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-01-08 | — | — | EP | disclosed |
| US-5521170-A | VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-28 | — | — | US | disclosed |
| EP-0620216-A1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |