SCHEMBL6972816

SCHEMBL6972816

C=CC(I)C=C(C)C(=O)O

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
PTGS1 P23219 1/20 0.30
AKR1C3 P42330 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL35840 0.79 ALDH1A1 (0.33) ALDH1A1PTGS1AKR1C3
SCHEMBL3268310 0.79 ALDH1A1 (0.33) ALDH1A1PTGS1AKR1C3
SCHEMBL1135819 0.77 ALDH1A1 (0.32) ALDH1A1PTGS1AKR1C3
SCHEMBL2119773 0.76 ALDH1A1 (0.35) ALDH1A1PTGS1AKR1C3
SCHEMBL7649350 0.74 ALDH1A1 (0.33) ALDH1A1PTGS1AKR1C3
SCHEMBL7056411 0.74 ALDH1A1 (0.33) ALDH1A1PTGS1AKR1C3
Vinyl Chloride SCHEMBL11358636 0.74
SCHEMBL8927710 0.74
SCHEMBL2593590 0.73 ALDH1A1 (0.32) ALDH1A1PTGS1AKR1C3
SCHEMBL6442139 0.73 ALDH1A1 (0.32) ALDH1A1PTGS1AKR1C3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6689588-B1 USE IN COLUMN CONTAINING THE IMMOBILIZED ALLIINASE AND COLLECTING PURE ALLICIN IN EFFLUENT; PURE ALLICIN HAS AS FOOD ADDITIVE OR PHARMACEUTICAL FOR INFECTIONS, THROMBOSIS OR HYPERLIPIDEMIA YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2004-02-10 US disclosed
EP-0904361-A1 IMMOBILIZED ALLIINASE AND CONTINUOUS PRODUCTION OF ALLICIN YEDA RESEARCH AND DEVELOPMENT COMPANY, LTD. (IL) 1999-03-31 EP disclosed
WO-1997039115-A1 IMMOBILIZED ALLIINASE AND CONTINUOUS PRODUCTION OF ALLICIN YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 1997-10-23 WO disclosed