SCHEMBL6972821

SCHEMBL6972821

CC(=CCC=CI)C(=O)O

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.35
GRIK2 Q13002 1/20 0.34
CD81 P60033 1/20 0.32
CYP2C9 P11712 1/20 0.32
PTGS1 P23219 1/20 0.31
PPARG P37231 1/20 0.31
FNTA P49354 1/20 0.31
FNTB P49356 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9486198 0.87 AKR1C3 (0.39) AKR1C3GRIK2CD81CYP2C9PTGS1
SCHEMBL9486204 0.87 AKR1C3 (0.39) AKR1C3GRIK2CD81CYP2C9PTGS1
SCHEMBL1774518 0.82 AKR1C3 (0.42) AKR1C3GRIK2CD81CYP2C9PTGS1
SCHEMBL1774515 0.82 AKR1C3 (0.42) AKR1C3GRIK2CD81CYP2C9PTGS1
SCHEMBL35841 0.81 AKR1C3 (0.35) AKR1C3GRIK2CD81CYP2C9PTGS1
SCHEMBL852778 0.81 AKR1C3 (0.35) AKR1C3GRIK2CD81CYP2C9PTGS1
SCHEMBL3126999 0.81 AKR1C3 (0.35) AKR1C3GRIK2CD81CYP2C9PTGS1
SCHEMBL700124 0.81 AKR1C3 (0.35) AKR1C3GRIK2CD81CYP2C9PTGS1
SCHEMBL1135821 0.81 TSHR (0.42) AKR1C3GRIK2PTGS1
SCHEMBL6442141 0.79 AKR1C3 (0.34) AKR1C3GRIK2CD81CYP2C9PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6689588-B1 USE IN COLUMN CONTAINING THE IMMOBILIZED ALLIINASE AND COLLECTING PURE ALLICIN IN EFFLUENT; PURE ALLICIN HAS AS FOOD ADDITIVE OR PHARMACEUTICAL FOR INFECTIONS, THROMBOSIS OR HYPERLIPIDEMIA YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2004-02-10 US disclosed
EP-0904361-A1 IMMOBILIZED ALLIINASE AND CONTINUOUS PRODUCTION OF ALLICIN YEDA RESEARCH AND DEVELOPMENT COMPANY, LTD. (IL) 1999-03-31 EP disclosed
WO-1997039115-A1 IMMOBILIZED ALLIINASE AND CONTINUOUS PRODUCTION OF ALLICIN YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 1997-10-23 WO disclosed