Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 9/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.53 |
| ▸ | CA9 | Q16790 | 4/20 | 0.48 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.37 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6981504 | 0.92 | PTGS2 (0.50) | PTGS2PTGS1CA9CA2CA12 | |
| SCHEMBL6981170 | 0.90 | PTGS2 (0.53) | PTGS2PTGS1 | |
| SCHEMBL6979993 | 0.90 | PTGS2 (0.55) | PTGS2PTGS1CA9CA2CA12 | |
| SCHEMBL6980759 | 0.86 | PTGS2 (0.55) | PTGS2PTGS1CA9CA2CA12 | |
| SCHEMBL6975328 | 0.86 | PTGS2 (0.66) | PTGS2PTGS1MAOAMAOB | |
| SCHEMBL6981010 | 0.84 | PTGS2 (0.52) | PTGS2PTGS1CA9CA2CA12 | |
| SCHEMBL6981724 | 0.82 | PTGS2 (0.50) | PTGS2PTGS1 | |
| SCHEMBL6980194 | 0.80 | PTGS2 (0.55) | PTGS2PTGS1MAPK14 | |
| SCHEMBL6974430 | 0.79 | PTGS2 (0.59) | PTGS2PTGS1CA9CA2CA12 | |
| SCHEMBL6974186 | 0.77 | PTGS2 (0.81) | PTGS2PTGS1MAPK14MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1105384-B1 | DIARYLBENZOPYRAN DERIVATIVES AS CYCLOOXYGENASE-2 INHIBITORS | PACIFIC CORP (KR) | 2003-03-26 | — | — | EP | claimed |
| US-6340694-B1 | Diarylbenzopyran derivatives as cyclooxygenase-2 inhibitors | PACIFIC CORPORATION (KR) | 2002-01-22 | — | — | US | claimed |
| CN-1323301-A | Diarylbenzopyran derivatives as cyclooxygenase-2 inhibitors | PACIFIC CORP (KR) | 2001-11-21 | — | — | CN | claimed |
| EP-1105384-A1 | DIARYLBENZOPYRAN DERIVATIVES AS CYCLOOXYGENASE-2 INHIBITORS | PACIFIC CORPORATION (KR) | 2001-06-13 | — | — | EP | claimed |
| WO-2000010993-A1 | DIARYLBENZOPYRAN DERIVATIVES AS CYCLOOXYGENASE-2 INHIBITORS | PACIFIC CORPORATION (KR) | 2000-03-02 | — | — | WO | claimed |
| EP-1105384-B1 | DIARYLBENZOPYRAN DERIVATIVES AS CYCLOOXYGENASE-2 INHIBITORS | PACIFIC CORP (KR) | 2003-03-26 | — | — | EP | disclosed |
| US-6340694-B1 | Diarylbenzopyran derivatives as cyclooxygenase-2 inhibitors | PACIFIC CORPORATION (KR) | 2002-01-22 | — | — | US | disclosed |
| CN-1323301-A | Diarylbenzopyran derivatives as cyclooxygenase-2 inhibitors | PACIFIC CORP (KR) | 2001-11-21 | — | — | CN | disclosed |
| EP-1105384-A1 | DIARYLBENZOPYRAN DERIVATIVES AS CYCLOOXYGENASE-2 INHIBITORS | PACIFIC CORPORATION (KR) | 2001-06-13 | — | — | EP | disclosed |
| WO-2000010993-A1 | DIARYLBENZOPYRAN DERIVATIVES AS CYCLOOXYGENASE-2 INHIBITORS | PACIFIC CORPORATION (KR) | 2000-03-02 | — | — | WO | disclosed |