Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | FDPS | P14324 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27753890 | 0.87 | KMT2A (0.38) | KMT2AMEN1HSP90AA1OPRD1BRD4 | |
| SCHEMBL697931 | 0.86 | KMT2A (0.40) | KMT2AMEN1HSP90AA1OPRD1BRD4 | |
| SCHEMBL700685 | 0.79 | KMT2A (0.42) | KMT2AMEN1HSP90AA1OPRD1BRD4 | |
| SCHEMBL4912536 | 0.78 | KMT2A (0.49) | KMT2AMEN1HSP90AA1OPRD1SMN1; SMN2 | |
| SCHEMBL697554 | 0.76 | MEN1 (0.39) | KMT2AMEN1HSP90AA1OPRD1RAB9A | |
| SCHEMBL697954 | 0.76 | MEN1 (0.39) | KMT2AMEN1HSP90AA1OPRD1RAB9A | |
| SCHEMBL11345241 | 0.76 | MEN1 (0.43) | KMT2AMEN1HSP90AA1OPRD1RAB9A | |
| SCHEMBL697630 | 0.74 | KMT2A (0.40) | KMT2AMEN1HSP90AA1OPRD1OPRK1 | |
| SCHEMBL696264 | 0.74 | TP53 (0.42) | KMT2AMEN1HSP90AA1OPRD1OPRK1 | |
| SCHEMBL697120 | 0.73 | MEN1 (0.44) | KMT2AMEN1HSP90AA1OPRD1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2423199-A1 | Substituted imidazoles and their use as pesticides | Pfizer Limited (GB) | 2012-02-29 | — | — | EP | disclosed |
| CN-101370786-B | Substituted imidazoles and their use as pesticides | PFIZER | 2012-01-11 | — | — | CN | disclosed |
| CN-101370786-A | Substituted imidazoles and their use as pesticides | PFIZER LTD (GB) | 2009-02-18 | — | — | CN | disclosed |