Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL696963 | 0.88 | MEN1 (0.41) | MEN1KMT2AOPRD1HSD17B10OPRK1 | |
| SCHEMBL697954 | 0.86 | MEN1 (0.39) | MEN1KMT2AOPRD1HSD17B10OPRK1 | |
| SCHEMBL11345241 | 0.84 | MEN1 (0.43) | MEN1KMT2AOPRD1HSD17B10OPRK1 | |
| SCHEMBL697374 | 0.84 | MEN1 (0.39) | TP53P2RX7MEN1KMT2AOPRD1 | |
| SCHEMBL697554 | 0.81 | MEN1 (0.39) | MEN1KMT2AOPRD1HSD17B10OPRK1 | |
| SCHEMBL697120 | 0.81 | MEN1 (0.44) | TP53P2RX7MEN1KMT2AOPRD1 | |
| SCHEMBL27733466 | 0.80 | OPRD1 (0.39) | TP53MEN1KMT2AOPRD1OPRK1 | |
| SCHEMBL697949 | 0.78 | KMT2A (0.37) | MEN1KMT2AOPRD1HSD17B10OPRK1 | |
| SCHEMBL17810214 | 0.77 | HSD17B10 (0.48) | MEN1KMT2AHSD17B10TDP1ALDH1A1 | |
| SCHEMBL27733620 | 0.76 | OPRD1 (0.39) | MEN1KMT2AOPRD1OPRK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2423199-A1 | Substituted imidazoles and their use as pesticides | Pfizer Limited (GB) | 2012-02-29 | — | — | EP | disclosed |
| CN-101370786-B | Substituted imidazoles and their use as pesticides | PFIZER | 2012-01-11 | — | — | CN | disclosed |
| EP-1981853-B1 | SUBSTITUTED IMIDAZOLES AND THEIR USE AS PESTICIDES | PFIZER LTD (GB) | 2011-04-13 | — | — | EP | disclosed |
| CN-101370786-A | Substituted imidazoles and their use as pesticides | PFIZER LTD (GB) | 2009-02-18 | — | — | CN | disclosed |