Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLA1 | P09884 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 4/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
| ▸ | EZH2 | Q15910 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6693414 | 0.86 | POLA1 (0.51) | POLA1KCNH2ENPP2ABCB1 | |
| SCHEMBL6692334 | 0.85 | POLA1 (0.52) | POLA1KCNH2ENPP2ABCB1MEN1 | |
| SCHEMBL6979490 | 0.82 | POLA1 (0.53) | POLA1KCNH2ENPP2ABCB1MEN1 | |
| SCHEMBL6694266 | 0.81 | POLA1 (0.54) | POLA1KCNH2ENPP2ABCB1MEN1 | |
| SCHEMBL6699742 | 0.78 | POLA1 (0.59) | POLA1KCNH2ABCB1MEN1KMT2A | |
| SCHEMBL6694571 | 0.75 | POLA1 (0.56) | POLA1KCNH2ENPP2ABCB1MEN1 | |
| SCHEMBL6697394 | 0.75 | POLA1 (0.59) | POLA1KCNH2ABCB1MEN1KMT2A | |
| SCHEMBL6980565 | 0.74 | KCNH2 (0.44) | POLA1KCNH2ENPP2EZH2 | |
| SCHEMBL6693410 | 0.73 | POLA1 (0.54) | POLA1KCNH2ENPP2ABCB1MEN1 | |
| SCHEMBL6699283 | 0.72 | POLA1 (0.53) | POLA1KCNH2ABCB1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1265873-B1 | 4-OXO-1,4-DIHYDRO-3-CINNOLINECARBOXAMIDES AS ANTIVIRAL AGENTS | UPJOHN CO (US) | 2003-10-15 | — | — | EP | disclosed |