Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 7/20 | 0.44 |
| ▸ | POLA1 | P09884 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | EZH2 | Q15910 | 2/20 | 0.38 |
| ▸ | CCR5 | P51681 | 1/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6974853 | 0.92 | KCNH2 (0.47) | KCNH2POLA1ALDH1A1ENPP2 | |
| SCHEMBL6693414 | 0.86 | POLA1 (0.51) | KCNH2POLA1ALDH1A1ENPP2 | |
| SCHEMBL6692334 | 0.81 | POLA1 (0.52) | KCNH2POLA1ALDH1A1ENPP2 | |
| SCHEMBL6667762 | 0.80 | MEN1 (0.42) | KCNH2POLA1ALDH1A1 | |
| SCHEMBL6694266 | 0.77 | POLA1 (0.54) | KCNH2POLA1ALDH1A1ENPP2 | |
| SCHEMBL6670577 | 0.77 | TSHR (0.47) | KCNH2POLA1ENPP2 | |
| SCHEMBL6699742 | 0.76 | POLA1 (0.59) | KCNH2POLA1ALDH1A1 | |
| SCHEMBL6667472 | 0.74 | MEN1 (0.41) | KCNH2POLA1ENPP2 | |
| SCHEMBL6669289 | 0.74 | NPC1 (0.40) | KCNH2POLA1ENPP2 | |
| SCHEMBL6972970 | 0.74 | POLA1 (0.41) | KCNH2POLA1EZH2ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1265873-B1 | 4-OXO-1,4-DIHYDRO-3-CINNOLINECARBOXAMIDES AS ANTIVIRAL AGENTS | UPJOHN CO (US) | 2003-10-15 | — | — | EP | claimed |