Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | AHR | P35869 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | BLM | P54132 | 3/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CCR1 | P32246 | 1/20 | 0.33 |
| ▸ | CCR5 | P51681 | 1/20 | 0.33 |
| ▸ | CCR8 | P51685 | 1/20 | 0.33 |
| ▸ | METAP1 | P53582 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.33 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27827268 | 0.81 | SMN1; SMN2 (0.42) | SMN1; SMN2L3MBTL1AHRCHRM2CYP1A2 | |
| SCHEMBL22863374 | 0.78 | SMN1; SMN2 (0.50) | SMN1; SMN2L3MBTL1AHRCHRM2CYP1A2 | |
| SCHEMBL4028599 | 0.77 | SMN1; SMN2 (0.41) | SMN1; SMN2L3MBTL1AHRCHRM2CYP1A2 | |
| SCHEMBL5148545 | 0.74 | SMN1; SMN2 (0.50) | SMN1; SMN2L3MBTL1AHRCHRM2CYP1A2 | |
| Ammonia Solution, Strong SCHEMBL27641252 | 0.74 | SMN1; SMN2 (0.50) | SMN1; SMN2L3MBTL1AHRCHRM2CYP1A2 | |
| SCHEMBL12934595 | 0.74 | SMN1; SMN2 (0.50) | SMN1; SMN2L3MBTL1AHRCHRM2CYP1A2 | |
| SCHEMBL12229498 | 0.73 | SMN1; SMN2 (0.50) | SMN1; SMN2L3MBTL1AHRCHRM2CYP1A2 | |
| SCHEMBL31645911 | 0.72 | SMN1; SMN2 (0.58) | SMN1; SMN2L3MBTL1AHRCHRM2CYP1A2 | |
| SCHEMBL29349628 | 0.72 | SMN1; SMN2 (0.58) | SMN1; SMN2L3MBTL1AHRCHRM2CYP1A2 | |
| SCHEMBL29080 | 0.72 | SMN1; SMN2 (0.58) | SMN1; SMN2L3MBTL1AHRCHRM2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1000046-B1 | PIPERAZINE DERIVATIVES ACTIVE ON THE LOWER URINARY TRACT | RECORDATI CHEM PHARM (CH) | 2003-11-26 | — | — | EP | disclosed |