Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 11/20 | 1.00 |
| ▸ | HTR1A | P08908 | 9/20 | 0.56 |
| ▸ | HTR1B | P28222 | 6/20 | 0.56 |
| ▸ | HTR2A | P28223 | 7/20 | 0.55 |
| ▸ | HTR2C | P28335 | 5/20 | 0.55 |
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.55 |
| ▸ | HTR7 | P34969 | 4/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | HTR6 | P50406 | 3/20 | 0.55 |
| ▸ | HTR2B | P41595 | 2/20 | 0.55 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.55 |
| ▸ | HTR5A | P47898 | 2/20 | 0.55 |
| ▸ | MPO | P05164 | 1/20 | 0.55 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.55 |
| ▸ | HTR3B | O95264 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | DRD1 | P21728 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7818127 | 0.99 | HTR1D (0.97) | HTR1DHTR1AHTR1BHTR2AHTR2C | |
| SCHEMBL6963613 | 0.84 | HTR1D (0.72) | HTR1DHTR1AHTR1BHTR2AHTR2C | |
| SCHEMBL6962933 | 0.82 | HTR1D (0.69) | HTR1DHTR1BHTR2AMPO | |
| SCHEMBL6962932 | 0.80 | SLC6A4 (0.66) | HTR1DHTR6 | |
| SCHEMBL23701768 | 0.78 | HTR1D (0.64) | HTR1DTSHRCYP2C9NPSR1KMT2A | |
| SCHEMBL30220806 | 0.78 | HTR1D (0.66) | HTR1DHTR1AHTR1BHTR2AHTR2C | |
| SCHEMBL31543643 | 0.78 | TRPV1 (0.64) | HTR1DHTR1ACYP1A2TSHRHTR2B | |
| SCHEMBL8198319 | 0.76 | HTR1D (0.61) | HTR1DHTR1AHTR1BHTR2AMPO | |
| SCHEMBL18509432 | 0.74 | HPGD (0.63) | HTR1DHTR1AHTR1BHTR2CHTR7 | |
| SCHEMBL6965288 | 0.74 | HTR1D (0.60) | HTR1DHTR1AHTR1BHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0944595-B1 | 5-CYCLO INDOLE COMPOUNDS AS 5-HT1D RECEPTOR LIGANDS | NPS ALLELIX CORP (CA) | 2003-10-01 | — | — | EP | claimed |