Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAP | Q12884 | 3/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.42 |
| ▸ | DPP4 | P27487 | 8/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.38 |
| ▸ | PREP | P48147 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5206039 | 1.00 | FAP (0.46) | FAPESR2PTPN1DPP4HDAC8 | |
| SCHEMBL5202232 | 0.89 | HDAC8 (0.47) | FAPPTPN1DPP4HDAC8DPP8 | |
| SCHEMBL5206014 | 0.89 | FAP (0.52) | FAPDPP4DPP8DPP9DPP7 | |
| SCHEMBL5206796 | 0.86 | DPP4 (0.44) | FAPPTPN1DPP4DPP8DPP9 | |
| SCHEMBL5208196 | 0.85 | HDAC8 (0.50) | FAPDPP4HDAC8 | |
| SCHEMBL7988406 | 0.83 | DPP4 (0.48) | FAPESR2PTPN1DPP4HDAC8 | |
| SCHEMBL7988401 | 0.83 | DPP4 (0.48) | FAPESR2PTPN1DPP4HDAC8 | |
| SCHEMBL864823 | 0.76 | PTPN1 (0.54) | ESR2PTPN1HDAC8 | |
| SCHEMBL30254985 | 0.76 | PTPN1 (0.54) | ESR2PTPN1HDAC8 | |
| SCHEMBL29502321 | 0.76 | PTPN1 (0.54) | ESR2PTPN1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100371323-C | Cyanopyrrolidine derivatives | TAISHO PHARMACEUTICAL CO LTD (JP) | 2008-02-27 | — | — | CN | disclosed |
| CN-1298703-C | Cyanopyrrolidine Derivatives | TAISHO PHARMACENTICAL CO LTD (JP) | 2007-02-07 | — | — | CN | disclosed |
| CN-1772733-A | Cyanopyrrolidine derivatives | TAISHO PHARMACEUTICAL CO LTD (JP) | 2006-05-17 | — | — | CN | disclosed |
| CN-1715269-A | Cyanopyrrolidine derivatives | TAISHO PHARMACEUTICAL CO LTD (JP) | 2006-01-04 | — | — | CN | disclosed |
| CN-1474809-A | Cyanopyrrolidine Derivatives | ������ҩ��ʽ���� | 2004-02-11 | — | — | CN | disclosed |
| EP-1333025-A1 | CYANOPYRROLIDINE DERIVATIVES | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2003-08-06 | — | — | EP | disclosed |