Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NOS1 | P29475 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | QPCT | Q16769 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6980301 | 0.91 | TSHR (0.46) | CYP19A1TSHRNOS1GAAKMT2A | |
| SCHEMBL6979646 | 0.90 | TSHR (0.52) | TSHRGAAKMT2AQPCTPGR | |
| SCHEMBL6979770 | 0.89 | FNTA (0.46) | CYP19A1TSHRGAAKMT2AQPCT | |
| SCHEMBL6978590 | 0.89 | QPCT (0.49) | CYP19A1TSHRGAAKMT2AQPCT | |
| SCHEMBL6977516 | 0.88 | PGR (0.58) | TSHRGAAKMT2AQPCTPGR | |
| SCHEMBL6976593 | 0.87 | TSHR (0.49) | TSHRGAAKMT2AQPCTPGR | |
| SCHEMBL6979128 | 0.87 | KMT2A (0.51) | TSHRGAAKMT2AQPCTPGR | |
| SCHEMBL6981436 | 0.87 | CYP1A2 (0.51) | TSHRGAAKMT2AQPCTPGR | |
| SCHEMBL6980755 | 0.87 | TSHR (0.54) | CYP19A1TSHRGAAKMT2AQPCT | |
| Hydrochloric Acid SCHEMBL7127430 | 0.86 | TSHR (0.48) | TSHRGAAKMT2AQPCTPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1346992-A1 | Quinazoline derivatives, process for their preparation and pharmaceutical compositions containing them | Les Laboratoires Servier (FR) | 2003-09-24 | — | — | EP | disclosed |