Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3796963 | 0.87 | NOTUM (0.51) | NOTUMALDH1A1NPC1CYP1A2CYP2C19 | |
| SCHEMBL7476539 | 0.86 | NOTUM (0.49) | NOTUMALDH1A1SMN1; SMN2TSHRHTT | |
| SCHEMBL13108777 | 0.83 | NOTUM (0.48) | NOTUMALDH1A1SMN1; SMN2TSHRHTT | |
| SCHEMBL5523654 | 0.78 | NOTUM (1.00) | NOTUMALDH1A1SMN1; SMN2NPC1LMNA | |
| SCHEMBL10167044 | 0.78 | NOTUM (1.00) | NOTUMALDH1A1SMN1; SMN2NPC1LMNA | |
| SCHEMBL2586534 | 0.78 | NOTUM (1.00) | NOTUMALDH1A1SMN1; SMN2NPC1LMNA | |
| SCHEMBL5523649 | 0.77 | NOTUM (0.68) | NOTUMALDH1A1SMN1; SMN2NPC1LMNA | |
| SCHEMBL16350248 | 0.77 | NOTUM (0.68) | NOTUMTP53 | |
| SCHEMBL4707127 | 0.77 | NOTUM (0.68) | NOTUMTP53 | |
| SCHEMBL21172540 | 0.75 | NOTUM (0.71) | NOTUMALDH1A1SMN1; SMN2NPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1142162-C | Bicyclic oxazolidinones as antibacterial agents | �������Ŷ���Լ��������˾ | 2004-03-17 | — | — | CN | disclosed |
| EP-1181288-B1 | BICYCLIC OXAZOLIDINONES AS ANTIBACTERIAL AGENT | UPJOHN CO (US) | 2003-07-30 | — | — | EP | disclosed |
| CN-1353709-A | Bicyclic oxazolidinones as antibacterial agents | PHARMACIA & UP JOHN CO (US) | 2002-06-12 | — | — | CN | disclosed |
| US-6387896-B1 | GRAMNEGATIVE, GRAMPOSITVE BACTERIA | PHARMACIA & UPJOHN CO. | 2002-05-14 | — | — | US | disclosed |