Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6973769 | 0.86 | NOTUM (0.64) | NOTUMHSD17B3SMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL3796963 | 0.78 | NOTUM (0.51) | NOTUMALDH1A1NPC1CYP1A2CYP2C19 | |
| SCHEMBL26262448 | 0.77 | GAA (0.46) | GAAMAPTTSHREPHX2 | |
| SCHEMBL397465 | 0.77 | GAA (0.46) | GAAMAPTTSHREPHX2 | |
| SCHEMBL22417606 | 0.77 | GAA (0.46) | GAAMAPTTSHREPHX2 | |
| SCHEMBL13108777 | 0.71 | NOTUM (0.48) | NOTUMSMN1; SMN2ALDH1A1TSHRHTT | |
| SCHEMBL10167044 | 0.67 | NOTUM (1.00) | NOTUMMAPTSMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL2586534 | 0.67 | NOTUM (1.00) | NOTUMMAPTSMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL5523654 | 0.67 | NOTUM (1.00) | NOTUMMAPTSMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL28253303 | 0.67 | GAA (0.44) | GAAMAPTTSHREPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1181288-A1 | BICYCLIC OXAZOLIDINONES AS ANTIBACTERIAL AGENT | PHARMACIA & UPJOHN COMPANY (US) | 2002-02-27 | — | — | EP | disclosed |
| WO-2000073301-A1 | BICYCLIC OXAZOLIDINONES AS ANTIBACTERIAL AGENT | PHARMACIA & UPJOHN COMPANY (US) | 2000-12-07 | — | — | WO | disclosed |