Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 2/20 | 0.39 |
| ▸ | PDE4A | P27815 | 2/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | DHPS | P49366 | 1/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5917803 | 0.84 | NPSR1 (0.46) | THRBDHPSDPP4KDM4EMEN1 | |
| SCHEMBL6399457 | 0.82 | SOAT1 (0.37) | THRATHRBSOAT1PTPN11PTPN1 | |
| SCHEMBL27875103 | 0.80 | SOAT1 (0.50) | THRATHRBSOAT1PTPN1TLR8 | |
| SCHEMBL27938548 | 0.80 | KDM4E (0.49) | MCHR1THRATHRBSOAT1PTPN11 | |
| SCHEMBL9068422 | 0.80 | KDM4E (0.49) | MCHR1THRATHRBSOAT1PTPN11 | |
| SCHEMBL28780749 | 0.79 | KDM4E (0.50) | THRATHRBSOAT1PTPN11PTPN1 | |
| SCHEMBL6054722 | 0.78 | PTPN11 (0.46) | PDE5APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL10597509 | 0.78 | PTPN11 (0.49) | MCHR1THRATHRBSOAT1PTPN11 | |
| SCHEMBL10596912 | 0.78 | PTPN11 (0.49) | MCHR1THRATHRBSOAT1PTPN11 | |
| SCHEMBL10597744 | 0.78 | PTPN11 (0.49) | MCHR1THRATHRBSOAT1PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8815218-B2 | Cosmetic or dermatological preparation | DR. STRAETMANS GMBH (DE) | 2014-08-26 | — | — | US | disclosed |
| US-20120128610-A1 | COSMETIC OR DERMATOLOGICAL PREPARATION | EVONIK OPERATIONS GMBH (DE) | 2012-05-24 | — | — | US | disclosed |
| EP-2421614-A1 | COSMETIC OR DERMATOLOGICAL PREPARATION | Dr. Straetmans GmbH (DE) | 2012-02-29 | — | — | EP | disclosed |
| WO-2010121759-A1 | COSMETIC OR DERMATOLOGICAL PREPARATION | DR. STRAETMANS GMBH (DE) | 2010-10-28 | — | — | WO | disclosed |
| EP-1723944-A1 | Cosmetic and dermatological sunscreens comprising chemical UV-screens and glyceryl triheptanoate | Dr. Streatmans Chemische Produktion GmbH (DE) | 2006-11-22 | — | — | EP | disclosed |