Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 5/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diethylene Glycol Monoethyl Ether SCHEMBL6065116 | 0.90 | THRB (0.34) | SOAT1PTPN11THRATHRBKDM4E | |
| SCHEMBL697379 | 0.82 | PDE5A (0.39) | SOAT1PTPN1PTPN11THRATHRB | |
| SCHEMBL627672 | 0.80 | CYP1A2 (0.39) | KDM4EALDH1A1CYP1A2HPGDCYP2C19 | |
| SCHEMBL27875103 | 0.78 | SOAT1 (0.50) | SOAT1PTPN1THRATHRBKDM4E | |
| SCHEMBL31099296 | 0.76 | SOAT1 (0.45) | SOAT1PTPN1PTPN11CYP1A2CYP2C19 | |
| SCHEMBL27615672 | 0.75 | SOAT1 (0.55) | SOAT1PTPN1THRATHRB | |
| SCHEMBL1372005 | 0.74 | LMNA (0.36) | PTPN11THRATHRBCYP1A2MAPT | |
| SCHEMBL3382014 | 0.73 | PTPN11 (0.36) | PTPN11THRATHRBALDH1A1MAPT | |
| SCHEMBL4248262 | 0.73 | SOAT1 (0.40) | SOAT1PTPN1PTPN11THRATHRB | |
| SCHEMBL1722952 | 0.72 | PAX8 (0.35) | PTPN11MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050129756-A1 | UV-stable, liquid or semisolid transdermal pharmaceutical preparation with light sensitive active ingredient | SCHERING AG (DE) | 2005-06-16 | — | — | US | disclosed |