Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.51 |
| ▸ | RAD52 | P43351 | 4/20 | 0.44 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.44 |
| ▸ | MME | P08473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.40 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.39 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL6964014 | 0.90 | ACHE (0.51) | ACHERAD52SMARCA2MMEMAPK1 | |
| Maleic Acid SCHEMBL6964004 | 0.90 | ACHE (0.51) | ACHERAD52SMARCA2MMEMAPK1 | |
| Maleic Acid SCHEMBL6973815 | 0.85 | ACHE (0.54) | ACHERAD52SMARCA2MMEMAPK1 | |
| Fumaric Acid SCHEMBL6973849 | 0.85 | ACHE (0.54) | ACHERAD52SMARCA2MMEMAPK1 | |
| Maleic Acid SCHEMBL6967317 | 0.85 | ACHE (0.54) | ACHERAD52SMARCA2MMERAB9A | |
| Fumaric Acid SCHEMBL6967326 | 0.85 | ACHE (0.54) | ACHERAD52SMARCA2MMERAB9A | |
| SCHEMBL6976514 | 0.84 | ACHE (0.60) | ACHERAD52SMARCA2MMEMAPK1 | |
| Maleic Acid SCHEMBL6976308 | 0.83 | ACHE (0.52) | ACHERAD52SMARCA2MMEMAPK1 | |
| Fumaric Acid SCHEMBL6976317 | 0.83 | ACHE (0.52) | ACHERAD52SMARCA2MMEMAPK1 | |
| Fumaric Acid SCHEMBL6975157 | 0.82 | KDM4E (0.51) | ACHERAD52SMARCA2MMEMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0870765-B1 | AMINOTHIAZOLE DERIVATIVES, DRUG CONTAINING THE SAME AND INTERMEDIATE IN THE PRODUCTION OF THE COMPOUNDS | ZERIA PHARM CO LTD (JP) | 2003-11-19 | — | — | EP | disclosed |
| US-5981557-A | HAVING IMPROVING EFFECTS ON THE DYSMOTILITY IN THE GASTROINTESTINAL TRACT | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1999-11-09 | — | — | US | disclosed |
| EP-0870765-A1 | AMINOTHIAZOLE DERIVATIVES, DRUG CONTAINING THE SAME AND INTERMEDIATE IN THE PRODUCTION OF THE COMPOUNDS | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1998-10-14 | — | — | EP | disclosed |