Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 19/20 | 0.63 |
| ▸ | CTSL | P07711 | 8/20 | 0.53 |
| ▸ | CTSB | P07858 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6964214 | 0.96 | CTSS (0.68) | CTSSCTSLCTSB | |
| SCHEMBL6973583 | 0.94 | CTSS (0.60) | CTSSCTSLCTSB | |
| SCHEMBL6964222 | 0.92 | CTSS (0.67) | CTSSCTSLCTSB | |
| SCHEMBL6974066 | 0.90 | CTSS (0.61) | CTSSCTSLCTSB | |
| SCHEMBL6107904 | 0.89 | CTSS (0.69) | CTSSCTSLCTSB | |
| SCHEMBL6968559 | 0.89 | CTSS (0.69) | CTSSCTSLCTSB | |
| SCHEMBL6967206 | 0.88 | CTSS (0.58) | CTSSCTSLCTSB | |
| SCHEMBL6976139 | 0.86 | CTSS (0.64) | CTSSCTSLCTSB | |
| SCHEMBL6106303 | 0.85 | CTSS (0.75) | CTSSCTSLCTSB | |
| SCHEMBL14383646 | 0.85 | CTSS (0.75) | CTSSCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1218372-B1 | NOVEL HETEROCYCLIC COMPOUNDS USEFUL AS REVERSIBLE INHIBITORS OF CYSTEINE PROTEASES | BOEHRINGER INGELHEIM PHARMA (US) | 2003-07-02 | — | — | EP | claimed |