Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6973993 | 1.00 | HSP90AA1 (0.39) | HSP90AA1ALDH1A1SMN1; SMN2LMNAHPGD | |
| SCHEMBL6964074 | 0.87 | HSP90AA1 (0.42) | HSP90AA1ALDH1A1SMN1; SMN2LMNAHPGD | |
| SCHEMBL6973778 | 0.87 | SMN1; SMN2 (0.38) | HSP90AA1ALDH1A1SMN1; SMN2LMNAHPGD | |
| SCHEMBL6973783 | 0.87 | SMN1; SMN2 (0.38) | HSP90AA1ALDH1A1SMN1; SMN2LMNAHPGD | |
| SCHEMBL6972288 | 0.82 | PDE4A (0.37) | HSP90AA1ALDH1A1SMN1; SMN2LMNAHPGD | |
| SCHEMBL6972294 | 0.82 | PDE4A (0.37) | HSP90AA1ALDH1A1SMN1; SMN2LMNAHPGD | |
| SCHEMBL6961068 | 0.82 | KDM4E (0.39) | ALDH1A1LMNAHPGDPOLBKDM4E | |
| SCHEMBL6961065 | 0.82 | KDM4E (0.39) | ALDH1A1LMNAHPGDPOLBKDM4E | |
| SCHEMBL6969992 | 0.82 | KDM4E (0.39) | KDM4ENPSR1GAA | |
| SCHEMBL6969990 | 0.82 | KDM4E (0.39) | KDM4ENPSR1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786455-B1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO (JP) | 2003-12-03 | — | — | EP | disclosed |
| US-6147097-A | METHOD FOR TREATING AIDS | SHIONOGI & CO., LTD. (JP) | 2000-11-14 | — | — | US | disclosed |