Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | CFTR | P13569 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | HPGD | P15428 | 5/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6973783 | 1.00 | SMN1; SMN2 (0.38) | SMN1; SMN2HSP90AA1CFTRIRAK4ALDH1A1 | |
| SCHEMBL6973701 | 0.88 | SMN1; SMN2 (0.40) | SMN1; SMN2HSP90AA1CFTRIRAK4ALDH1A1 | |
| SCHEMBL6972288 | 0.87 | PDE4A (0.37) | SMN1; SMN2HSP90AA1ALDH1A1HPGDLMNA | |
| SCHEMBL6972294 | 0.87 | PDE4A (0.37) | SMN1; SMN2HSP90AA1ALDH1A1HPGDLMNA | |
| SCHEMBL6973998 | 0.87 | HSP90AA1 (0.39) | SMN1; SMN2HSP90AA1ALDH1A1HPGDLMNA | |
| SCHEMBL6973993 | 0.87 | HSP90AA1 (0.39) | SMN1; SMN2HSP90AA1ALDH1A1HPGDLMNA | |
| SCHEMBL6964470 | 0.86 | CFTR (0.42) | SMN1; SMN2CFTRALDH1A1LMNAPOLB | |
| SCHEMBL6964467 | 0.86 | CFTR (0.42) | SMN1; SMN2CFTRALDH1A1LMNAPOLB | |
| SCHEMBL6975800 | 0.85 | MAPT (0.35) | SMN1; SMN2ALDH1A1HPGDLMNAPOLB | |
| SCHEMBL6975797 | 0.85 | MAPT (0.35) | SMN1; SMN2ALDH1A1HPGDLMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786455-B1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO (JP) | 2003-12-03 | — | — | EP | disclosed |
| US-6147097-A | METHOD FOR TREATING AIDS | SHIONOGI & CO., LTD. (JP) | 2000-11-14 | — | — | US | disclosed |