Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 5/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7081706 | 0.93 | — | — | |
| SCHEMBL6974559 | 0.90 | PTPRA (0.32) | — | |
| SCHEMBL6960274 | 0.90 | MAPT (0.34) | SLC6A9ADORA2AADORA1 | |
| SCHEMBL7078551 | 0.89 | SLC6A9 (0.33) | SLC6A9ADORA2AADORA1 | |
| SCHEMBL7084827 | 0.86 | SLC6A9 (0.34) | SLC6A9ADORA2AADORA1 | |
| SCHEMBL6969928 | 0.86 | CYP1A2 (0.35) | — | |
| SCHEMBL7164320 | 0.86 | RHEB (0.31) | — | |
| SCHEMBL7084286 | 0.86 | MAPK13 (0.30) | — | |
| SCHEMBL7081199 | 0.85 | SLC6A9 (0.33) | SLC6A9 | |
| SCHEMBL6967986 | 0.85 | SLC6A9 (0.34) | SLC6A9ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786455-B1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO (JP) | 2003-12-03 | — | — | EP | disclosed |
| US-6147097-A | METHOD FOR TREATING AIDS | SHIONOGI & CO., LTD. (JP) | 2000-11-14 | — | — | US | disclosed |
| US-5910506-A | IMIDAZOLE DERIVATIVES, E.G.5-(3,5-DICHLOROPHENYLTHIO)-1,2-DIMETHYL-4-ISOPROPYL-1H-IMIDAZOLE; VIRICIDES; AIDS; NONTOXIC | SHIONOGI & CO., LTD. (JP) | 1999-06-08 | — | — | US | disclosed |
| EP-0786455-A1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1997-07-30 | — | — | EP | disclosed |