SCHEMBL697440

SCHEMBL697440

Cc1cc(C(O)c2ncc[nH]2)ccc1F

nearest known ligand 0.54

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F2RL1 P55085 20/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL698494 0.84 ADRA2A (0.51) F2RL1
SCHEMBL3529538 0.83 F2RL1 (0.44) F2RL1
SCHEMBL24241667 0.80 F2RL1 (0.50) F2RL1
SCHEMBL27733492 0.79 F2RL1 (0.47) F2RL1
SCHEMBL3529536 0.76 TAAR1 (0.39) F2RL1
SCHEMBL697637 0.76 F2RL1 (0.53) F2RL1
SCHEMBL697367 0.75 F2RL1 (0.47) F2RL1
SCHEMBL4909884 0.74 F2RL1 (0.49) F2RL1
SCHEMBL696452 0.74 F2RL1 (0.49) F2RL1
SCHEMBL7676472 0.73 CYP17A1 (0.46) F2RL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2423199-A1 Substituted imidazoles and their use as pesticides Pfizer Limited (GB) 2012-02-29 EP disclosed
EP-1981853-B1 SUBSTITUTED IMIDAZOLES AND THEIR USE AS PESTICIDES PFIZER LTD (GB) 2011-04-13 EP disclosed