Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.42 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 2/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TOP2A | P11388 | 1/20 | 0.30 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6211264 | 0.91 | MEN1 (0.54) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL9411016 | 0.90 | MEN1 (0.55) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL6973407 | 0.88 | KCNH2 (0.56) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL6973414 | 0.88 | KCNH2 (0.56) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL6973421 | 0.88 | KCNH2 (0.56) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL6983582 | 0.85 | CACNA1F (0.40) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL6983293 | 0.85 | CACNA1F (0.40) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL6984330 | 0.85 | ALDH1A1 (0.56) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL9411085 | 0.83 | MEN1 (0.56) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL9411007 | 0.82 | KDM4E (0.57) | MEN1KMT2AKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0603887-B1 | Bicyclic amine derivatives | DAIICHI SEIYAKU CO (JP) | 2003-10-01 | — | — | EP | claimed |