Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 11/20 | 0.69 |
| ▸ | FNTB | P49356 | 11/20 | 0.69 |
| ▸ | PGGT1B | P53609 | 2/20 | 0.53 |
| ▸ | HTR2C | P28335 | 5/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PLAUR | Q03405 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6982870 | 0.91 | FNTA (0.68) | FNTAFNTBPGGT1BHTR2CCYP3A4 | |
| SCHEMBL6982604 | 0.90 | FNTA (0.61) | FNTAFNTBPGGT1BHTR2CCYP3A4 | |
| SCHEMBL6977393 | 0.90 | FNTA (0.57) | FNTAFNTBPGGT1BHTR2CCYP3A4 | |
| SCHEMBL6979480 | 0.90 | FNTA (0.57) | FNTAFNTBPGGT1BHTR2CCYP3A4 | |
| SCHEMBL6975380 | 0.89 | FNTA (0.56) | FNTAFNTBPGGT1BHTR2CCYP3A4 | |
| SCHEMBL6984228 | 0.88 | FNTA (0.55) | FNTAFNTBPGGT1BHTR2CCYP3A4 | |
| SCHEMBL6982219 | 0.88 | FNTA (0.57) | FNTAFNTBPGGT1BHTR2CCYP3A4 | |
| SCHEMBL6977285 | 0.87 | FNTA (0.53) | FNTAFNTBPGGT1BMEN1ALDH1A1 | |
| SCHEMBL6982224 | 0.86 | KDM4E (0.53) | FNTAFNTBPGGT1BCYP3A4MEN1 | |
| SCHEMBL6980781 | 0.85 | FNTA (0.52) | FNTAFNTBPGGT1BHTR2CCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1045846-B1 | IMIDAZOLE DERIVATIVES HAVING AN INHIBITORY ACTIVITY FOR FARNESYL TRANSFERASE AND PROCESS FOR PREPARATION THEREOF | LG CHEMICAL LTD (KR) | 2003-05-02 | — | — | EP | claimed |
| US-6268363-B1 | ANTITUMOR | LG CHEMICAL LTD. (KR) | 2001-07-31 | — | — | US | claimed |
| EP-1045846-A1 | IMIDAZOLE DERIVATIVES HAVING AN INHIBITORY ACTIVITY FOR FARNESYL TRANSFERASE AND PROCESS FOR PREPARATION THEREOF | LG CHEMICAL LIMITED (KR) | 2000-10-25 | — | — | EP | claimed |
| WO-1999028315-A1 | IMIDAZOLE DERIVATIVES HAVING AN INHIBITORY ACTIVITY FOR FARNESYL TRANSFERASE AND PROCESS FOR PREPARATION THEREOF | LG CHEMICAL LTD. (KR) | 1999-06-10 | — | — | WO | claimed |