Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 9/20 | 0.41 |
| ▸ | F10 | P00742 | 5/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 11/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 10/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 10/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | PLG | P00747 | 3/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | C1S | P09871 | 1/20 | 0.39 |
| ▸ | PLAT | P00750 | 1/20 | 0.39 |
| ▸ | F7 | P08709 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6975241 | 0.86 | C1S (0.41) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL6967577 | 0.81 | F2 (0.44) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL6976964 | 0.78 | F2 (0.48) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL4667657 | 0.78 | ALDH1A1 (0.46) | — | |
| SCHEMBL7061403 | 0.73 | F10 (0.64) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL6981412 | 0.72 | PTPN1 (0.53) | F2F10PRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL14632602 | 0.72 | F7 (0.46) | F2F10PRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL14632393 | 0.71 | PLAU (0.47) | F2F10PRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL14632411 | 0.71 | PLAU (0.47) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL10856126 | 0.71 | PLG (0.61) | F2F10PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1284961-A1 | GLYCINAMIDES | MERCK PATENT GmbH (DE) | 2003-02-26 | — | — | EP | disclosed |
| WO-2001092219-A1 | GLYCINAMIDES | MERCK PATENT GMBH (DE) | 2001-12-06 | — | — | WO | disclosed |