Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1A | P07327 | 6/20 | 0.50 |
| ▸ | ADH1C | P00326 | 4/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SHBG | P04278 | 1/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | ADH1B | P00325 | 1/20 | 0.30 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
| ▸ | PHGDH | O43175 | 1/20 | 0.30 |
| ▸ | MGLL | Q99685 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6975521 | 0.98 | ADH1A (0.48) | ADH1AADH1CCYP1A2 | |
| SCHEMBL1678881 | 0.87 | — | — | |
| SCHEMBL6975259 | 0.86 | ADH1A (0.42) | ADH1AADH1CCYP1A2ALDH1A1 | |
| SCHEMBL6969286 | 0.84 | ADH1A (0.41) | ADH1AADH1CCYP1A2 | |
| SCHEMBL6977261 | 0.80 | ADH1A (0.46) | ADH1AADH1CCYP1A2ALDH1A1SHBG | |
| SCHEMBL5253027 | 0.78 | ADH1A (0.52) | ADH1AADH1CCYP1A2ALDH1A1HRH4 | |
| SCHEMBL25510772 | 0.78 | ADH1A (0.52) | ADH1AADH1CCYP1A2ALDH1A1HRH4 | |
| SCHEMBL6975475 | 0.77 | — | — | |
| SCHEMBL17046153 | 0.76 | ADH1A (0.50) | ADH1AADH1CCYP1A2ALDH1A1HRH4 | |
| SCHEMBL24158306 | 0.75 | ADH1A (0.54) | ADH1AADH1CCYP1A2ALDH1A1SHBG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0870765-B1 | AMINOTHIAZOLE DERIVATIVES, DRUG CONTAINING THE SAME AND INTERMEDIATE IN THE PRODUCTION OF THE COMPOUNDS | ZERIA PHARM CO LTD (JP) | 2003-11-19 | — | — | EP | disclosed |
| US-5981557-A | HAVING IMPROVING EFFECTS ON THE DYSMOTILITY IN THE GASTROINTESTINAL TRACT | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1999-11-09 | — | — | US | disclosed |
| EP-0870765-A1 | AMINOTHIAZOLE DERIVATIVES, DRUG CONTAINING THE SAME AND INTERMEDIATE IN THE PRODUCTION OF THE COMPOUNDS | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1998-10-14 | — | — | EP | disclosed |