Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 8/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.43 |
| ▸ | KDM5A | P29375 | 1/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8381369 | 0.93 | DNM1 (0.62) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL6139846 | 0.93 | DNM1 (0.62) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL9332356 | 0.93 | DNM1 (0.62) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL6973646 | 0.92 | DNM1 (0.46) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL8372336 | 0.92 | CHRM2 (0.50) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL6968772 | 0.90 | CHRM2 (0.44) | DNM1MEN1KMT2AALDH1A1TSHR | |
| Putrescine SCHEMBL22442866 | 0.90 | DNM1 (0.57) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL11765113 | 0.90 | DNM1 (0.50) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL15557660 | 0.90 | CHRM2 (0.48) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL578737 | 0.90 | DNM1 (0.55) | DNM1MEN1KMT2AALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0870765-B1 | AMINOTHIAZOLE DERIVATIVES, DRUG CONTAINING THE SAME AND INTERMEDIATE IN THE PRODUCTION OF THE COMPOUNDS | ZERIA PHARM CO LTD (JP) | 2003-11-19 | — | — | EP | disclosed |
| US-5981557-A | HAVING IMPROVING EFFECTS ON THE DYSMOTILITY IN THE GASTROINTESTINAL TRACT | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1999-11-09 | — | — | US | disclosed |
| EP-0870765-A1 | AMINOTHIAZOLE DERIVATIVES, DRUG CONTAINING THE SAME AND INTERMEDIATE IN THE PRODUCTION OF THE COMPOUNDS | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1998-10-14 | — | — | EP | disclosed |