SCHEMBL6971046

SCHEMBL6971046

COc1ccc2c(c1)c(OCCOc1ccc(C(N)=O)cc1)nn2Cc1cccc(N)c1

nearest known ligand 0.45

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 2/20 0.45
CNR2 P34972 2/20 0.45
ACHE P22303 1/20 0.45
PLA2G2A P14555 11/20 0.45
PTGER4 P35408 2/20 0.42
HCAR3 P49019 1/20 0.41
ABHD6 Q9BV23 1/20 0.41
PARP10 Q53GL7 1/20 0.40
CHEK2 O96017 1/20 0.38
ALDH1A1 P00352 1/20 0.38
GAA P10253 1/20 0.38
PKM P14618 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6973836 0.90 CNR2 (0.54) CNR1CNR2ACHEPLA2G2APTGER4
Hydrochloric Acid SCHEMBL6968039 0.89 CNR2 (0.53) CNR1CNR2ACHEPLA2G2APTGER4
SCHEMBL6978241 0.78 CNR2 (0.49) CNR1CNR2ACHEPLA2G2APTGER4
SCHEMBL6975679 0.78 CNR2 (0.49) CNR1CNR2ACHEPLA2G2APTGER4
SCHEMBL6973326 0.77 CNR2 (0.58) CNR1CNR2ACHEPLA2G2AABHD6
SCHEMBL6974448 0.76 CNR1 (0.48) CNR1CNR2ACHEPLA2G2A
SCHEMBL6979571 0.74 CNR2 (0.56) CNR1CNR2ACHEPLA2G2AABHD6
SCHEMBL6975035 0.74 PLA2G2A (0.43) CNR1CNR2ACHEPLA2G2APTGER4
Hydrochloric Acid SCHEMBL6977850 0.72 PLA2G2A (0.42) CNR1CNR2ACHEPLA2G2APTGER4
SCHEMBL6968297 0.72 CNR2 (0.49) CNR1CNR2ACHEPLA2G2AABHD6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1077947-B1 NOVEL 1,5 AND 3-O-SUBSTITUTED 1H-INDAZOLES WITH ANTI-ASTHMATIC, ANTI-ALLERGIC, ANTI-INFLAMMATORY, IMMUNO-MODULATING AND NEURO-PROTECTIVE EFFECT, METHOD FOR THE PRODUCTION AND USE THEREOF AS MEDICAMENTS DRESDEN ARZNEIMITTEL (DE) 2003-09-03 EP claimed
EP-1077947-B1 NOVEL 1,5 AND 3-O-SUBSTITUTED 1H-INDAZOLES WITH ANTI-ASTHMATIC, ANTI-ALLERGIC, ANTI-INFLAMMATORY, IMMUNO-MODULATING AND NEURO-PROTECTIVE EFFECT, METHOD FOR THE PRODUCTION AND USE THEREOF AS MEDICAMENTS DRESDEN ARZNEIMITTEL (DE) 2003-09-03 EP disclosed