SCHEMBL6975752

SCHEMBL6975752

[CH2]C(C)(CCCC(=O)OCC)C(=O)OCC

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.48
CYP4F2 P78329 3/20 0.42
CYP4A11 Q02928 3/20 0.42
PKM P14618 2/20 0.42
THRB P10828 1/20 0.42
HTT P42858 1/20 0.41
NR1I2 O75469 1/20 0.40
PGR P06401 1/20 0.40
ADORA3 P0DMS8 1/20 0.40
PTGS2 P35354 1/20 0.40
PDE4D Q08499 1/20 0.40
GAA P10253 2/20 0.40
MGAM O43451 1/20 0.39
SI P14410 1/20 0.39
MGAM2 Q2M2H8 1/20 0.39
L3MBTL1 Q9Y468 2/20 0.38
ALDH1A1 P00352 2/20 0.38
MEN1 O00255 1/20 0.38
MAPT P10636 1/20 0.38
KMT2A Q03164 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2116494 0.81 CYP4F2 (0.62) CYP1A2CYP4F2CYP4A11PKMTHRB
SCHEMBL16358138 0.79 CYP1A2 (0.53) CYP1A2CYP4F2CYP4A11NR1I2PGR
SCHEMBL8165697 0.79 CYP1A2 (0.57) CYP1A2CYP4F2CYP4A11NR1I2PGR
SCHEMBL20076307 0.78 CYP1A2 (0.52) CYP1A2CYP4F2CYP4A11PKMTHRB
SCHEMBL9263994 0.77 CYP1A2 (0.47) CYP1A2CYP4F2CYP4A11PKMTHRB
SCHEMBL27526995 0.77 CYP1A2 (0.55) CYP1A2CYP4F2CYP4A11NR1I2PGR
SCHEMBL27435507 0.77 PKM (0.43) CYP1A2CYP4F2CYP4A11PKMTHRB
SCHEMBL25290311 0.76 CYP1A2 (0.50) CYP1A2CYP4F2CYP4A11PKMTHRB
SCHEMBL12480501 0.76 CYP1A2 (0.50) CYP1A2CYP4F2CYP4A11PKMTHRB
SCHEMBL21052369 0.76 CYP4F2 (0.66) CYP1A2CYP4F2CYP4A11PKMTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1272486-A1 METHOD FOR PRODUCING 7-(PYRAZOLE-3-YL) BENZOXAZOLES BASF AKTIENGESELLSCHAFT (DE) 2003-01-08 EP disclosed
WO-2001068644-A1 METHOD FOR PRODUCING 7-(PYRAZOLE-3-YL) BENZOXAZOLES BASF AKTIENGESELLSCHAFT (DE) 2001-09-20 WO disclosed